Viraday

Description

Viraday consists of three molecules combined in a fixed-dose combination for managing HIV-1 infection in adults. The molecules include tenofovir disoproxil (TDF) 300 mg, Efavirenz (EFV) 600 mg, and Emtricitabine (FTC) 200 mg. In terms of dosage, the triple-combination drug is taken orally as a single tablet once daily without food. The bedtime dosing schedule is preferred over others, as it eliminates out possibility of procuring symptoms of the nervous system.

Viraday (TDF 300 mg + EFV 600 mg + FTC 200 mg) is avoided in patients with moderate to severe renal (kidney) impairment. It is indicated as a complete regimen for preventing the multiplication of HIV cells in the body. However, it does not necessarily cure the infection.

Initial testing before starting Viraday (TDF 300 mg + EFV 600 mg + FTC 200 mg):

• •  Hepatitis B viral (HBV) infection testing
• •  Chronic kidney disease testing
• •  Testing to determine the functioning of the liver
• •  Pregnancy testing in patients with child-bearing potential or their associated partners

Side-effects and Warnings of Viraday (TDF 300 mg + EFV 600 mg + FTC 200 mg):

Serious side-effects:

• •  Lactic acidosis (High amount of lactic acid in the blood)
• •  Hepatomegaly (Enlarged liver)
• •  Steatosis (Excessive fats in the liver)
• •  Recurrence of HBV infection
• •  Psychiatric side-effects like depression, unusual thoughts, angry behavior, suicidal tendencies, anxiety, aggressive behavior, delusions and psychosis-like symptoms
• •  Thinning of bones (Decreased bone mineral density)

Common side-effects: These side-effects can be reduced after a few weeks of therapy

• •  Headache
• •  Rashes
• •  Dizziness
• •  Difficult in sleeping and concentrating
• •  Infrequent dreams
• •  Tiredness
• •  Gas
• •  Upset stomach
• •  Vomiting
• •  Diarrhea

Other possible side-effects:

• •  Increased amounts of fat in the upper back, neck, breast, and trunk regions
• •  Skin discoloration with small freckles and spots
• •  Inflammation from previous infections
• •  Inflammation of the pancreas
• •  Swelling of the face, lips, tongue or throat due to an allergic reaction to drugs
• •  Shortness of breath
• •  Stomach pain
• •  Indigestion
• •  Weakness

Note: These are not all side effects of Viraday (TDF 300 mg + EFV 600 mg + FTC 200 mg). If you need more information, please consult your doctor.  

Warnings and Precautions:

There are certain complications wherein either Viraday (TDF 300 mg + EFV 600 mg + FTC 200 mg) needs to be stopped or used cautiously. These complications have been mentioned in the table below along with their causes.