Maraviroc

Maraviroc

• Classification - HIV-1 medicine

What is Maraviroc?

It is an anti-retroviral medicine used for HIV-1 infection.

Uses of Maraviroc

• HIV-1 infections
• Resistant or intolerant to other anti-retrovirals.
• CCR5 tropic HIV-1 infection

How does Maraviroc work?

• It inhibits the binding of the virus to the receptor. Downregulating its action.

Common side effects

• Cough
• Fever
• Flue
• Dizziness
• Muscle pain
• Joint pain
• Fatigue
• GIT upset

Serious side effects

• Severe liver toxicity
• High risk of infections
• Low blood pressure
• Irregular heartbeat
• Coordination issues
• Mood changes

Precautions of Maraviroc

• To be used cautiously in patients with -
• Liver disorders
• Heart disorders
• Kidney dysfunctions
• Low blood pressure
• Weak immunity

Contraindications

• Allergy to the drug
• Breastfeeding mothers
• Pregnant women

Warning

• To be used under medical prescription only
• It can't be used as a single treatment for HIV-1.
• Effective against CCR5-tropic HIV-1 infection only.

Important Monitoring Considerations

Monitor-

• Liver functions
• Low blood pressure
• Increased risk of infections
• Skin rashes
• Fever
• Viral count
• CD4+ count

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