Sorafenib
Sorafenib
Classification – Anticancer Medicine
What is Sorafenib?
It is an anticancer medication used for advanced cancers of the liver and kidney that cannot be treated with surgery, or for differentiated thyroid cancer that has recurred or spread to other parts of the body.
Uses of Sorafekast
- • Hepatocellular carcinoma
- • Renal cell carcinoma
- • Thyroid carcinoma (Radioactive iodine-refractory differentiated thyroid cancer)
How does Sorafekast work?
It is a multikinase inhibitor.
It inhibits several protein kinases.
It inhibits new blood vessel formation, cuts off the blood supply and oxygen to cancer cells, causing cancer cell death.
Common Side Effects
- • High blood pressure
- • Weight loss
- • Hair loss
- • Diarrhea
- • Skin rashes
- • Mouth ulcers
- • Pain in the abdomen
- • Delayed wound healing
Serious Side Effects
- • Gastrointestinal bleeding
- • Risk of blood clotting
- • Heart complications - heart attack, stroke
- • QT prolongation – irregular heartbeats
- • Severely high blood pressure
- • Skin peeling and ulceration
- • Visual changes, headaches, and seizures
Precautions
To be used cautiously in patients having:
- • Advanced liver dysfunctions
- • Hypertensive patients
- • Cardiovascular disorders
- • Blood disorders
- • Planning surgery
- • Thyroid disorders
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to Sorafenib or any excipients
- • Breastfeeding mothers
- • Pregnant women
Warnings
To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.
Important Safety and Monitoring Information
Regularly monitor cardiac functions, hepatic, renal functions, skin colorations, thyroid functions, and bleeding functions.
Formulations based on "Sorafenib" (9)
Mapsonib 200mg Tablet
Sorafenib 200mg
Mapsonib 200 is sorafenib 200 mg, manufactured by AMPS Biotech Pvt Ltd.
Nexavar 200mg Tablet
Sorafenib 200mg
It is manufactured by Bayer Zydus Pharma.
Shilfenib 200mg Tablet
Sorafenib 200mg
What is the Shilfenib (sorafenib) tablet?
Sorepto 200mg Tablet
Sorafenib 200mg
Gandhi Medicos is the drug supplier of Lupin products.
Sorafina
Sorafenib
Used as an anti-cancer treatment for liver /kidney cancer or relapsed thyroid cancer.
Sorafekast
Sorafenib
It is an anticancer medicine that is used for advanced or recurrent liver, kidney, or thyroid cancer.
Adtrinib 200mg Tablet
Sorafenib 200mg
Tyrosine kinase inhibitors like Adtrinib 200mg Tablet are used to treat various types of cancer, including those of the liver, kidney, and thyroid.
Sorafenat
Sorafenib
The Sorafenat (Sorafenib) is an anti-cancer medicine specifically used to treat liver cancer, thyroid cancer, and kidney cancer. Cancer can be defined as a disease in which the body's cells grow ab...
Soranib Tablet
Sorafenib
It is known to fight against the tumors of kidney, liver and thyroid. Scientifically, Soranib 200 mg (sorafenib) has anti-tumor properties like,