Tacrolimus 0.
Tacrolimus 1mg
- Classification - Organ Transplant Medicine
What is Tacrolimus?
Tacrolimus is an organ transplant medicine, widely used for post-transplant care and prophylaxis of organ rejection.
- Best-selling Transplant Medicine- Xgraf -1
Uses of Tacrolimus
- Prophylaxis for organ transplant.
- Post-transplant therapy
- Kidney transplant
- Liver transplant
- Heart transplant
Working of Tacrolimus -
- It suppresses the activity of T cells and lowers the immune response.
- Accepts the organ transplants
Benefits:
- Faster onset
- Potent immune-suppression
- Long-term graft survival
Common side effects
- Increases creatinine
- Skin rashes
- Headache
- GIT upset
- Nausea,
- Diarrhea
- High calcium levels
- Low potassium levels
- Tiredness
Serious side effects
- Renal toxicity
- Severe infections
- Seizures, encephalopathy
- Bone marrow suppression
- Metabolic dysfunctions
- Cardiovascular side effects
- Arrhythmias, high blood pressure
- Lymph proliferative disorder (PTLD)
Precautions:
- To be used cautiously used in-
- Elderly Patients
- Bleeding disorders
- Liver disorders
- Kidney diseases
- Active infections- HIV, Hepatitis
- Diabetics
- Hypertension patients
- Neurological disorders
Safety instructions
Maintain contraception during the treatment.
Avoid live vaccines (MMR, Varicella) due to a compromised immune system.
Contraindications
- Pregnant women and breastfeeding mothers.
- Hypersensitivity or allergic reaction to the drug or its excipients.
Warnings
- To be used under medical prescription.
Drug Interactions
- Antiviral
- Antibiotics
- TB medicines
- And other immune suppressants
- Cardiovascular drugs -calcium channel blockers
- Antifungal
- Grapefruit juice
Important Monitoring Considerations
- Monitor for -
- Total blood count
- Liver and kidney functions
- Neurological functions
- Blood pressure, blood glucose
- Cardiac functions
- Dose Monitoring is required.
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Formulations based on "Tacrolimus 0." (33)
Tacrograf 2 Capsule
tacrolimus (2.0mg)
Classification - Immunosuppressant medicine
Pangraf 0.5 Capsule
Tacrolimus (0.5mg)
With other medications, Pangraf 0.5 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body’s immune system so ...
Rolitrans 0.5mg Capsule
Tacrolimus (0.5mg)
With other medications, Rolitrans 0.5mg Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body’s immune system...
Tacrocord 0.5 Capsule
Tacrolimus (0.5mg)
With other medications, Tacrocord 0.5 capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body’s immune system s...
Tacrograf 0.5 Capsule
Tacrolimus (0.5mg)
With other medications, Tacrograf 0.5 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body’s immune system s...
Tacsant 0.5mg Capsule
Tacrolimus (0.5mg)
With other medications, Tacsant 0.5mg Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body’s immune system s...
Vingraf 0.5 Capsule
Tacrolimus (0.5mg)
With other medications, Vingraf 0.5 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body’s immune system so ...
Prograf 0.5mg Capsule
Tacrolimus (0.5mg)
With other medications, Prograf 0.5mg Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body’s immune system s...
Takfa 0.5 Capsule
Tacrolimus (0.5mg)
With other medications, Takfa 0.5 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body’s immune system so th...
Tacroren 0.5 Capsule
Tacrolimus (0.5mg)
With other medications, Tacroren 0.5 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body’s immune system so...
Tacromus 0.5 Capsule
Tacrolimus (0.5mg)
With other medications, Tacromus 0.5 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body’s immune system so...
Tacrol 1mg Capsule
Tacrolimus (1mg)
With other medications, Tacrol 1mg Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so t...
Nefgraf 2mg Capsule
Tacrolimus (2mg)
With other medications, Nefgraf 2mg Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so ...
Xgraf 2 Capsule
Tacrolimus (2mg)
With other medications, Xgraf 2 is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so that the new...
Tacromus 2mg Capsule
Tacrolimus (2mg)
With other medications, Tacromus 2mg Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so...
Takfa 2 Capsule
Tacrolimus (2mg)
With other medications, Takfa 2 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so that...
Vingraf 2mg Capsule
Tacrolimus (2mg)
With other medications, Vingraf 2mg Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so ...
Biomus 2mg Capsule
Tacrolimus (2mg)
With other medications, Biomus 2mg Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so t...
Tacren 2 Capsule
Tacrolimus (2mg)
With other medications, Tacren 2 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so tha...
Fujigraf 2mg Capsule
Tacrolimus (2mg)
With other medications, Fujigraf 2mg Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so...
Imunotac 2mg Capsule
Tacrolimus (2mg)
With other medications, Imunotac 2mg Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so...
Pangraf 2 Capsule
tacrolimus (2.0mg)
With other medications, Pangraf 2 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so th...
Xgraf 0.5 Capsule
Tacrolimus (0.5mg)
With other medications, Xgraf 0.5 is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so that the n...
Prograf 1mg Hard Capsule
Tacrolimus (1mg)
With other medications, Prograf 1mg Hard Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune syste...
Xgraf 1 Capsule
Tacrolimus (1mg)
With other medications, Xgraf 1 is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so that the new...
Tacromus 1 Capsule
Tacrolimus (1mg)
With other medications, Tacromus 1 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so t...
Takfa 1 Capsule
Tacrolimus (1mg)
With other medications, Takfa 1 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so that...
Vingraf 1 Capsule
Tacrolimus (1mg)
With other medications, Vingraf 1 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so th...
Biomus 1 Capsule
Tacrolimus (1mg)
With other medications, Biomus 1 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so tha...
Tacroren 1 Capsule
Tacrolimus (1mg)
With other medications, Tacroren 1 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so t...
Tacsant 1mg Capsule
Tacrolimus (1mg)
With other medications, Tacsant 1mg Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so ...
Tacrograf 1 Capsule
Tacrolimus (1mg)
With other medications, Tacrograf 1 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so ...
Pangraf 1 Capsule
Tacrolimus (1mg)
With other medications, Pangraf 1 Capsule is used to prevent your body from rejecting a new organ (such as a liver, kidney, or heart) after transplant. So it weakens your body's immune system so th...