Abacavir 300 mg
Abacavir 300 mg
- Classification: HIV medicine
What is Abacavir?
It is widely used against HIV-1 Infection. It forms a part of anti-retroviral therapy.
Uses -
- It is used in combination with other HIV medicines (ART therapy)
- Used to treat HIV-1 infections
- Delays progression to aids
How does it work?
- It mimics the natural DNA bases, inhibits DNA multiplication.
- Terminates DNA chain elongation
- Inhibit viral cell growth
Benefits
- Reduces viral load to undetectable levels
- Reduces the risk of transmission
- Improves immunity
- Reduce the risk of severe infections
- Effective in both children and adults
- Well tolerated
Common side effects
- Nausea
- Headache
- Reduced appetite
- Skin rashes
- Nasal congestion
- Cough
- Diarrhea
- Mild fever
- Tiredness
Serious side effects
- Liver toxicity
- Increased risk of heart attack
- Swollen fatty liver
- Lactic acidosis
- Yellowish urine, jaundice
Contraindications
- Severe liver dysfunction.
- Hypersensitivity or allergy to drug components.
Warnings
- To be used under medical prescription.
Do not discontinue abruptly, Hepatitis B co-infections may cause serious liver flare-ups.
Important monitoring considerations
- Liver functions
- Cardiovascular functions
- Viral count
- Blood count -CD4 cell count
- Lactic acid buildup
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