Lenalid 10MG
Rated 5.00 out of 5 based on 12 customer ratings
(12 customer reviews)
Packaging Type | Bottle |
Dose/Strength | 10MG Tablets |
Packaging Size | 30 capsules |
Brand | |
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Salt |
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Category: Anti Cancer Drugs
Description
Lenalid 10 mg (Lenalidomide) is an anti-cancer drug used in patients suffering from disorders or cancers of the blood. Lenalid 10 mg (Lenalidomide) is preferably indicated for myelodysplastic syndrome (MDS), a group of cancer wherein blood cells become immature leading to overcrowded unhealthy blood cells. Lenalidomide is speculated to work its action by stopping the growth of blood vessels that nourishes these cancerous cells (Anti-angiogenesis).
Additional properties of Lenalidomide:
- It affects the process of division and multiplication of cancerous cells (Cell-proliferation)
- It restricts the production of chemicals that are used in the communication of cancerous cells
- If triggers immune response thereby determining the working of the immune system (Immunomodulatory effects)
- It assists in altering the production of chemicals important for growth and survival of cancerous cells i.e. cytokines (Antineoplastic)
- It can affect the genes responsible for carrying out processes of self-destruction (apoptosis) and metabolism.
Administration of Lenalid 10 mg (Lenalidomide):
Lenalid 10 mg (Lenalidomide) is given orally in a form of 10 mg dosage once daily in the morning or evening. Once swallowed, the dose is completely absorbed (bioavailable) within 6 hours of administration. Lenalidomide is further metabolized in the liver and distributed throughout the cancerous region. Once it completes its action, subsequently, more than 50% of the dose is expelled from the body within 3 to 5 hours predominantly in the form of urine (90%). In patients with kidney (renal) problems, approximately 40% of lenalidomide is excreted during a single dialysis session.
An initial dose of Lenalid 10 mg (Lenalidomide) for renal impairment patients with MDS:
As the drug is not readily excreted from the kidney, the initial dosage of lenalidomide needs to be adjusted in patients with moderate or severe problems in the kidney with MDS. The adjustment is very crucial for appropriate drug exposure in such patients. The table below will show the initial dose of lenalidomide for patients in different stages of kidney problems with MDS.
Table: Starting dose of Lenalidomide for renal impairment patients with MDS
Category of renal impairment | Dosage |
Moderate | 5 mg once daily |
Severe | 2.5 mg once daily |
End-stage disease | 2.5 mg once daily after the dialysis |
When should Lenalid 10 mg (Lenalidomide) be avoided or used cautiously?
- If the patients had negative pregnancy tests (2) before taking lenalidomide, it is important to resist having sex for before and 4 weeks after treatment
- If patients have any sort of bleeding complications (hematologic toxicity), dose reduction or adjustment is highly recommended
- If patients have risks of heart problems (deep vein thrombosis or pulmonary embolism)
- If patients are suffering from a condition where the cancerous cells are overkilled, spraying their contents in the blood (tumor lysis syndrome)
- If patients have a risk of liver and kidney disease
- If patients are lactose intolerant, the dose should be altered accordingly as lenalidomide contains lactose
- If patients get allergic reactions from drugs or skin rashes, dose and frequency should be adjusted.
Most common side-effects of Lenalid 10 mg (Lenalidomide) in MDS patients:
- Decrease in platelets (Thrombocytopenia)
- Fever with other signs of infection (Febrile neutropenia)
- Tiredness (Fatigue)
- Irritation in nose and pharynx region in the neck (Nasopharyngitis)
- Shortness of breath (Dyspnea)
- Continuous itchiness of skin (Pruritus)
- Continuous itchiness of skin (Pruritus)
- Swelling caused due to unwanted gathering of fluids (peripheral edema)
- Joint pain (Arthralgia)
- Increased temperature of the body (Pyrexia)
- Sudden bleeding through the nose (Epistaxis)
Most common ones:
- Stomach problems like diarrhea, constipation
- Nausea
- Pain in back and muscles
- Rashes on skin
- Dizziness
- Headache
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12 reviews for Lenalid 10MG
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If you think you may have a medical emergency, call your doctor or go to the emergency department, or immediately. Gandhi Medicos does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on Gandhi Medicos. Reliance on any information provided by Gandhi Medicos, Gandhi Medicos employees, contracted writers, or medical professionals presenting content for publication to Gandhi Medicos is solely at your own risk.
The Site may contain health- or medical-related materials or discussions regarding sexually explicit disease states. If you find these materials offensive, you may not want to use our Site. The Site and its Content are provided on an "as is" basis.
Links to educational content not created by Gandhi Medicos are taken at your own risk. Gandhi Medicos is not responsible for the claims of external websites and education companies.
General Advisory:We advise you to stick to medication routine (or medication adherence), i.e. to take medications as prescribed – the right dose, at the right time, in the right way and frequency. Not taking medicines as prescribed by a doctor or instructed by a pharmacist could lead to disease getting worse, hospitalization, even death.
All Trademarks, Brands and Service marks that appear on this website belong to their respective owner.
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