Description
Paclikast -260 mg
Composition: Paclitaxel -260 mg
Classification: Anticancer Medicine
What is Paclitaxel?
It is a chemotherapy anti-cancer medicine, used against various cancers and solid tumors.
Uses of Paclikast
• Breast cancer
• Ovarian cancer
• AIDS related sarcoma
• Non-small cell lung cancer
• Pancreatic cancer
• Head and neck cancer
How Does It Work?
It inhibits the double-stranded DNA breakage to single-strand, inhibits the replication and multiplication of DNA.
Common Side Effects
• Tiredness
• Hair loss
• Increases the risk of infections
• Indigestion – diarrhea, constipation
• Hypotension
• Mouth ulcers
• Muscle and joint pain
• UTI
• Anemia
• Numbness of limbs, tingling in hands, fingers
Serious Side Effects
• Bone Marrow Suppression
• Slow heartbeat
• Shortness of breath
• Blood clot
• Chest pain
• Liver toxicity
• Local tissue injury
• Pain in the abdomen
Precautions
To be used cautiously in patients with –
• Liver disorders
• Renal disorders
• Hypertension patients
• Elderly patients
• Pre-existing infections
• Immune-compromised patients
• Adjuvant to myelosuppressive treatments
Contraindications
• Not to be used if any previous allergy or hypersensitivity to Paclitaxel or any excipients.
• Breastfeeding mothers
• Pregnant women
Warnings
To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.
Important safety and monitoring information
Regularly monitor blood count, hepatic, manage infection risks, cardiac functions, and early signs of peripheral neuropathy.
Storage
It should be stored at 2-8 degrees Celsius, protected from light.
Administration Instructions
• To be administered as a slow IV infusion only.
• Do not give as an IV push/bolus.
• To be used immediately after reconstitution.
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