Description
Tafnext 25mg
Composition : Tenofovir Alfenamide- 25mg
Classification: Hepatitis B Medicine
What is Tafnext?
It is an antiviral medicine that controls chronic Hepatitis B and HIV-1 infections.
Uses of Tafnext
• Chronic Hepatitis B
• As a combination therapy in HIV-1 infections
How does it work?
It inhibits the enzyme that causes viral replication and multiplication.
It causes natural viral cell death.
Benefits
• Targeted action, fewer side effects
• Significant viral suppression
• Lesser effect on kidney functions
• Improved liver functions
• Better bone mineral density
• Well tolerated
Common side effects
Nausea, dizziness, headache, digestive issues, tiredness, diarrhea, and abdominal pain.
Serious side effects
• Lactic Acidosis – unusual pain, breathing issues, irregular heartbeats, abdominal pain.
• Irregular heartbeat – Arrhythmia
• Deep or rapid breathing
• Enlarged fatty liver
• Severely low phosphate levels cause muscle weakness
• Pale hands and feet (blue coloration)
• Dark urine, yellow eyes, pale stool
• Fluid retention-swelling of joints
• Sudden inflammatory reaction on starting the treatment.
Precautions
To be used cautiously in patients with:
• Kidney disorders
• HIV—Co-infections
• Liver transplant
• Elderly Patients
• Postmenopausal women
• People at risk of osteoporosis
Contraindication—
• Not to be used if any previous allergy or hypersensitivity to tenovofir or any excipients.
• Breastfeeding mothers
• Pregnant women
• It should not be used as monotherapy for HIV patients
Warning
To be used under medical prescription only
Important Safety and Monitoring Information
• Regular monitoring of the liver function, renal function, and bone density.
• Screen for viral load and HIV infections before treatment initiation.
• Hepatitis B flares, if the medicine is abruptly discontinued.
Treatment Instructions
• It must be taken consistently to get effective viral suppression.
• Missing doses increase the risk of relapse and drug resistance.
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