Abacavir 300 mg

Classification: HIV medicine

What is Abacavir?

It is widely used against HIV-1 Infection. It forms a part of anti-retroviral therapy.

Uses

  • • It is used in combination with other HIV medicines (ART therapy)
  • • Used to treat HIV-1 infections
  • • Delays progression to AIDS

How does it work?

  • • It mimics the natural DNA bases, inhibits DNA multiplication
  • • Terminates DNA chain elongation
  • • Inhibits viral cell growth

Benefits

  • • Reduces viral load to undetectable levels
  • • Reduces the risk of transmission
  • • Improves immunity
  • • Reduces the risk of severe infections
  • • Effective in both children and adults
  • • Well tolerated

Common Side Effects

  • • Nausea
  • • Headache
  • • Reduced appetite
  • • Skin rashes
  • • Nasal congestion
  • • Cough
  • • Diarrhea
  • • Mild fever
  • • Tiredness

Serious Side Effects

  • • Liver toxicity
  • • Increased risk of heart attack
  • • Swollen fatty liver
  • • Lactic acidosis
  • • Yellowish urine, jaundice

Contraindications

  • • Severe liver dysfunction
  • • Hypersensitivity or allergy to drug components

Warnings

To be used under medical prescription.

Do not discontinue abruptly; Hepatitis B co-infections may cause serious liver flare-ups.

Important Monitoring Considerations

  • • Liver functions
  • • Cardiovascular functions
  • • Viral count
  • • Blood count – CD4 cell count
  • • Lactic acid buildup

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