Abiraterone Acetate 500mg

Classification: Anticancer Medicine

Abiraterone Acetate?

An oncology medicine that is widely used as a treatment for resistant prostate cancer.

Uses of Abiraterone

  • • Advanced Hormone-sensitive prostate cancer
  • • Castration-resistant prostate cancer (CRPC)

Working of Abiraterone Acetate

  • • Inhibits the secretion of testosterone.
  • • Testosterone causes cancer cell growth.
  • • Inhibits cancer cell proliferation.
  • • Shrinks the tumor.

Benefits of Abiraterone Acetate

  • • Delays disease progression.
  • • Improves survival rates in advanced-stage prostate cancer.
  • • Ease of convenience – can be taken orally.

Common Side Effects

  • • Tiredness
  • • Hypertension
  • • Joint pain
  • • Hot flashes
  • • Liver dysfunction – elevated liver enzymes
  • • Kidney dysfunction – fluid retention
  • • Urinary tract infection
  • • Hypokalemia

Serious Side Effects

  • • Hepatic toxicity
  • • Cardiovascular disorders
  • • Severe hypokalemia
  • • Adrenal crisis
  • • Fluid retention

Contraindications

Not to be used in patients:

  • • Hypersensitivity or allergy to drug components
  • • Abiraterone is not recommended for use in women.
  • • Breastfeeding mothers
  • • Pregnant women

Precautions of Abiraterone Acetate

  • • Cardiac abnormalities
  • • Hepatic impaired functions
  • • Renal impaired functions

Warnings

Prescription drug to be used under medical supervision.

Important Safety and Monitoring Information

Abiraterone requires regular monitoring for –

  • • Hematological functions – blood count
  • • Blood pressure
  • • Liver functions
  • • ECG, cardiac functions
  • • Regular monitoring of electrolytes

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