Afatinib Dimaleate 40mg
Classification – Anticancer Medicines
What is Afatinib Diamleate?
It is an oncology medicine used for respiratory cancer.
Uses
- • Non-small lung cancer
- • Advanced NSLC
- • Recurrent lung cancer
- • Mutations of the EGFR genes
Working of Afatinib Diamleate
It inhibits cancer proliferation and growth. It causes cancer cell starvation and death.
Benefits of using Afatinib Diamleate
- • Strong irreversible binding
- • Broad spectrum of activity
- • Slow disease progression
- • Used in failed chemotherapy
- • Better tolerated than chemotherapy
Common Side Effects
- • Diarrhea
- • Skin and nail changes
- • Mouth ulcers
- • Nausea
- • GIT upset
- • Reduced appetite
Serious Side Effects
- • Liver dysfunctions
- • Cardiovascular complications
- • Kidney dysfunctions
- • Loss of electrolytes
- • Dehydration
- • Lung toxicity – cough, difficulty in breathing
- • Blurred vision
Precautions
To be used cautiously in patients with:
- • Kidney dysfunctions
- • Liver dysfunctions
- • Hypertension
- • Eye issues
- • Heart disorders
- • Elderly
- • Dehydration
- • Concomitant use with diuretics and an EGFR inhibitor
Contraindications
Not to be used in patients-
- • Hypersensitivity or allergy to the drug composition
- • Pregnant and breastfeeding women
Warnings
Prescription drug to be used under medical supervision.
Important Safety and Monitoring Information
- • Blood pressure
- • Liver functions
- • Kidney functions
- • Lung functions
- • Skin rashes, itching
- • Dehydration
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