Carboplatin (150mg)
Classification: Anticancer Medicine
Carboplatin?
Used as an anticancer agent for the treatment of various cancers and solid tumors, offers fewer side effects than other platinum agents.
Uses of Carboplatin
- • Ovarian cancers
- • Endometrial cancer
- • Head and Neck Cancer
- • Palliative care for recurrent cancer
- • Cancer of the esophagus
- • Non-small cell lung cancer
- • Lung cancer
- • Breast cancer
How Does Carboplatin Work?
It causes crosslinking of the DNA strands, causing wrong binding and cancer cell death.
Common Side Effects
- • Alopecia
- • Weakness
- • Nausea
- • Diarrhea
- • Kidney dysfunctions
- • Liver dysfunctions
- • Dehydration
- • Anemia
- • Risk of infections
Serious Side Effects
- • Myelosuppression
- • Hepatic toxicity
- • Renal toxicity
- • Ototoxicity
Precautions
To be used cautiously in:
- • Renal disorders
- • Liver disease
- • Bleeding disorders
- • Hearing issues
- • Elderly patients
- • Bone marrow suppression
Contraindications
- • Hypersensitivity to carboplatin or any other platinum-containing compound
- • Bone marrow suppression
- • Breastfeeding mothers
- • Pregnant women
Important Handling Instructions
Due to its cytotoxic nature, carboplatin should be handled-
- • Wear gloves to reduce skin exposure
- • Wash off immediately if it comes in contact with the mucosal layer or the skin.
- • Carboplatin gets precipitated with aluminum needles or IV sets and causes loss of potency.
Warnings
To be used under the supervision of a doctor or oncologist.
Important Safety and Monitoring
It causes dose-dependent bone marrow suppression
- • Peripheral blood counts
- • Renal functions
- • Liver functions
- • Electrolyte balance
- • Ear functions
Storage
- • Store at 2-8°C
- • Protect from light
Administration Instructions
- • To be administered as an IV infusion (15-60 minutes)
- • Use immediately after reconstitution
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Highly prescribed and top-selling carboplatin formulation – Carbokast
