Cytarabine

Classification: Anticancer

What is Cytarabine?

It is an anticancer medicine used for different types of blood cancers.

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Uses of Cytarabine

  • • Myeloid leukemia
  • • Myelogenous leukemia
  • • Meningeal leukemia
  • • Lymphoblastic leukemia

How does Cytarabine work?

It inhibits the formation of cancer cells and stops DNA replication and angiogenesis.

Common Side Effects

  • • GIT troubles – vomiting, diarrhea
  • • Hair loss, risk of bleeding, mouth ulcers, skin rashes, stomach aches

Serious Side Effects

  • • Neurotoxicity – seizures, confusion
  • • Ocular toxicity – dry red eyes, blurred vision
  • • Bone marrow suppression – risk of bleeding
  • • Hepatotoxicity – elevated liver enzymes

Precautions

To be used cautiously in patients with:

  • • Pre-existing liver dysfunction
  • • Renal dysfunction
  • • Immune-compromised conditions
  • • Neurological disorders

Contraindications

  • • Allergy or hypersensitivity to Cytarabine or any component
  • • Breastfeeding mothers
  • • Pregnant women

Warnings

To be used under the supervision of a doctor or oncology specialist.

Important Safety and Monitoring Information

  • • Regularly monitor blood count, hepatic and neurological assessments, manage infection risks, and assess ocular and renal functions.

Storage

Store at 2-8°C, protected from light.

Administration Instructions

  • • To be administered as intrathecal, subcutaneous, or IV infusion.
  • • To be used immediately after reconstitution.

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