Dacarbazine
Classification: Anticancer Medicine
What is Dacarbazine?
It is a component of chemotherapy used against various cancers and solid tumors.
Top selling Dacarbazine – Dasakast
Uses of Dacarbazine
- Myeloid Leukemia (Chronic)
- Lymphoblastic leukemia (Acute)
Working of Dacarbazine
- It inhibits kinase enzymes and certain proteins.
- Slows down or stops the cancer cell growth.
Common Side Effects
- Fluid retention
- Lowering of blood count
- Nausea
- Diarrhea
- Skin ulcers and rashes
Serious Side Effects
- Risk of cardiac arrhythmia
- Bone marrow suppression
- Pulmonary Arterial Hypertension
Contraindications
Not to be used in patients –
- Hypersensitivity or allergic reaction to the drug or its excipients
- Breastfeeding mothers
- Pregnant women
Precautions
To be cautiously used in patients with –
- Bleeding disorder
- Heart diseases
- Liver disorder
- Kidney impairment
- Recent surgery or wound
- Disorders of the stomach
Toxicities
- Bone Marrow suppression – low blood count
- Pleural effusion – shortness of breath, fluid buildup around the lungs
- Hematological toxicity – bleeding risk, decreased platelet count
- Hepatotoxicity – elevated enzymes
- QT Prolongation – irregular heartbeats
Warnings
Prescription drug to be used under medical supervision.
Important Safety and Monitoring Information
Dacarbazine requires regular monitoring for hematological functions, blood pressure, liver functions, ECG, regular monitoring of electrolytes.
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At Gandhi Medicos, we are dedicated to transforming global cancer care by supplying authentic, affordable, and life-saving anticancer medicines to patients across the world.
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Gandhi Medicos — Your Trusted Partner in the Fight against Cancer.

