Composition

Dolutegravir (50mg), Lamivudine (300mg), Tenofovir disoproxil fumarate (300mg)

Classification

HIV Medicine

Why Dolutegravir, Lamivudine, and Tenofovir?

The combination is made to ease administration as a single oral dose, and it also offers synergistic effects to suppress HIV.

Uses

  • • HIV-1 infections

How does it work?

  • • Dolutegravir: Prevents genetic transmission into human immune cells.
  • • Lamivudine: Inhibits the formation of viral cell DNA.
  • • Tenofovir: Inhibits viral cell multiplication.

Benefits

  • • Powerful control of HIV
  • • Well tolerated
  • • Lowers the risk of drug resistance
  • • Fewer side-effects
  • • Improves immunity
  • • Prevents transmission
  • • Prevents HIV progression

Common Side Effects

  • • Insomnia
  • • Tiredness
  • • Headache
  • • Increased weight
  • • Skin rashes
  • • Abdominal pain
  • • Nausea
  • • Diarrhea
  • • Hyperlipidemia

Serious Side Effects

  • • Liver dysfunction
  • • Lactic acidosis
  • • Increased blood glucose
  • • Kidney dysfunctions
  • • Neurological side effects – depression / suicidal thoughts
  • • Bone density loss

Precautions

To be used cautiously in:

  • • People with diabetes
  • • Liver disorders
  • • Mental health conditions
  • • Elderly
  • • Kidney impairment
  • • Pregnant women

Drug Interactions

  • • Antacids
  • • Rifampicin
  • • Phenytoin
  • • Barbiturates
  • • Metformin
  • • Supplements containing Iron or Calcium

Contraindications

  • • Severe liver dysfunction
  • • Severe renal impairment
  • • Hypersensitivity or allergy to drug components
  • • Breastfeeding mothers
  • • Co-administration with nephrotoxic drugs

Warnings

  • • To be used under medical prescription
  • • Do not stop medication immediately, as it may flare up the previous hepatitis infection

Important Monitoring Considerations

  • • Liver function – elevated liver enzymes
  • • Viral loads (HIV, HBV)
  • • Neurological conditions
  • • Renal functions
  • • Blood glucose
  • • Weight
  • • CD4+ count

Gandhi Medicos: 19 Years of Legacy in HIV Care

Gandhi Medicos is the leading HIV medicine distributor and supplier to hospitals, HIV care centers, NGOs, and pharmacies worldwide.

  • ✅ 400+ Ethical Brands
  • ✅ 500+ Generic Options
  • ✅ Leading Exporter of Fixed-Dose HIV Combinations
  • ✅ 25,000+ Happy Customers
  • ✅ 3,000+ Monthly Orders

Why Choose Gandhi Medicos?

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