Entecavir
Classification: Hepatitis B Medicine
Entecavir?
It is an anti-viral medicine which is used for the treatment of Hepatitis B.
How does Entecavir work?
- • It inhibits DNA chain elongation
- • Causes viral cell death
Uses of Entecavir
- • It is used in Chronic Hepatitis B
- • Preventive care to prevent the recurrence of Hepatitis B
Benefits
- • Suppresses viral load
- • Can be used after a liver transplant
- • Can be used in HIV co-infection
- • In advanced liver disorders
Common Side Effects
- • Nausea
- • Dizziness
- • Headache
- • Digestive issues
- • Tiredness
- • Diarrhea
Serious Side Effects
- • Lactic acidosis – lactic acid buildup in blood, causing muscle pain, unusual tiredness
- • Enlarged fatty liver
- • Hepatitis B flare-ups
- • HIV co-infection may worsen
- • Renal dysfunctions
Precautions of Entecavir
To be used cautiously in patients with:
- • Kidney disorders
- • Liver dysfunction
- • Liver transplant
- • HIV co-infection
- • Pediatric population
- • Elderly patients
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to Entacavir or any excipients.
- • Breastfeeding mothers
- • Pregnant women
Warning
To be used under medical prescription only
Important Safety and Monitoring Information
- • Regular monitoring of liver function, renal function, and bone density
- • Always screen for viral load and HIV infections before and during the treatment
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