Ivabradine (7.5mg)

Classification: Cardiovascular Medicine

Ivabradine?

It is a medicine used for a fast cardiac rhythm or heart failure.

Uses

  • • Chronic heart failure
  • • Control heart rate
  • • Orthostatic tachycardia
  • • Chest pain

Working of Ivabradine

It works on the Sino-Atrial node, slowing down the fast heart rate.

Common Side Effects

  • • Slows down the heart rate
  • • Visual effects
  • • Dizziness
  • • Headaches
  • • Tiredness

Serious Side Effects

  • • Severely slow heart rate
  • • Irregular heart rhythm
  • • Low blood pressure
  • • Worsened angina
  • • QT prolongation

Benefits

  • • Lowers heart rate without lowering blood pressure
  • • Reduces chest pain
  • • Reduces the risk of hospitalization
  • • Improves exercise tolerance
  • • Well tolerated
  • • Can be used with other cardiac medicines

Precautions

  • • Atrial fibrillation
  • • Severe bradycardia
  • • Severely low blood pressure
  • • Liver disorders
  • • Elderly patients
  • • Conduction abnormalities

Contraindications

  • • Sino-atrial block
  • • 3rd degree heart block
  • • External pacemaker
  • • Unstable heart failure
  • • Use with other antiarrhythmic medications
  • • Allergy to the drug components
  • • Pregnant and breastfeeding women

Warnings

To be used under medical prescription.

Important Monitoring Considerations

Regularly monitor –

  • • Heart rate
  • • Heart rhythm
  • • Blood pressure
  • • Effects on the eye

Drug Interactions

  • • Antifungals
  • • Rifampicin
  • • Phenytoin
  • • Antiarrhythmics
  • • Beta blockers
  • • Diuretics
  • • Barbiturates

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