Lapatinib

Classification – Anticancer Medicine

What is Lapatinib?

It is an anticancer medicine that works against hormone-sensitive breast cancer.

Uses of Lapatinib

  • HER-2 positive breast cancer
  • Hormone-sensitive breast cancer

How does Lapatinib work?

  • Stops cancer multiplication and growth
  • Shrinks the tumor

Common Side Effects

  • Diarrhea
  • Nausea
  • Skin rashes
  • Reduced appetite
  • Hand–foot syndrome
  • Liver dysfunction
  • Heart dysfunction

Serious Side Effects

  • Severe diarrhea
  • Dehydration
  • Liver toxicity
  • Shortness of breath
  • Decreased heart function
  • Symptoms worsen due to tumor changes

Precautions

  • Liver disorders
  • Heart disorders
  • Lung disease
  • People prone to dehydration
  • Caution when used with other drugs like ketoconazole, phenytoin
  • Elderly

Contraindications

  • Should not be used in pregnant women and breastfeeding mothers
  • Hypersensitivity or allergy to drug components

Warnings

To be used under medical prescription.

Safety instructions

  • Maintain contraception during the treatment
  • Avoid live vaccines (MMR, Varicella) due to a compromised immune system

Important Monitoring Considerations

Monitor for-

  • Liver functions
  • Heart functions
  • Hydration status
  • Electrolyte balance

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