Lenalidomide
Classification – Anticancer medicine
What is Lenalidomide?
It is an immune-modulatory drug, used as an anti-neoplastic against various types of blood cancers.
Widely prescribed anticancer medicine – Lenakast
Uses of Lenalidomide
- • Relapsed /refractory multiple myeloma
- • Relapsed or refractory mantle cell lymphoma
- • Bone marrow disorders
Working of Lenalidomide work?
- • It improves the immune system
- • Inhibits the process of formation of new cells
- • Causes cell starvation and cell death
Common Side Effects
- • Low blood count
- • Weakness
- • Mouth ulcers
- • Skin rashes
- • Clots
- • Loss of appetite
- • GIT troubles – abdominal pain, diarrhea, constipation
Serious Side Effects
- • Myelosuppression
- • Severely low blood count
- • GIT perforation and bleeding
- • Thrombosis
- • Liver toxicity – jaundice, yellow skin, eyes
- • Kidney toxicity – electrolyte imbalance, reduced urination
- • Risk of severe infections
Contraindications
- • Allergy or hypersensitivity to drug components
- • Breastfeeding mothers
- • Pregnant women
Warnings
To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.
Precautions
To be used cautiously in patients with:
- • Kidney disorders
- • Liver dysfunctions
- • Chronic infections
- • Cardiovascular diseases
- • Weak immunity
- • Blood disorder
Important Safety and Monitoring Information
- • To monitor liver functions carefully- elevated liver enzymes
- • Kidney functions
- • Blood pressure
- • Blood count
- • Cardiac functions
- • Signs of neuropathy
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