Lenvatinib

Classification: Anticancer

Lenvatinib?

Lenvatinib is an anticancer medicine that is used for several advanced-stage cancers or metastatic cancers.

Uses of Lenvatinib

  • Advanced Kidney Cancer
  • Radioactive Iodine-Refractory Differentiated Thyroid Cancer
  • Advanced Hepatocellular Carcinoma
  • Endometrial Carcinoma

How Does Lenvatinib Work?

  • It is a multiple tyrosine kinase inhibitor
  • It blocks several kinase enzymes
  • Inhibits angiogenesis
  • Causes cancer cells to starve and die

Common side effects include –

  • High BP
  • Tiredness
  • Diarrhea
  • Nausea
  • Loss of appetite
  • Weight decline
  • Hand and foot syndrome
  • Pain in muscles and joints
  • Delayed wound healing

Serious Side Effects

These are dose-dependent side effects that can be managed by supportive care.

  • Dizziness, seizures, and confusion
  • Stroke or heart failure
  • Elevated liver enzymes, acute liver failure
  • GIT perforations
  • Internal bleeding
  • Thrombosis

Precautions

To be cautiously used in patients with –

  • Heart disease
  • Renal disorder
  • Liver disorder
  • Elderly patients

Contraindication

  • Allergy or hypersensitivity to Lenvatinib and its components
  • Breastfeeding mothers
  • Pregnant women

Warning

To be used under medical prescription only

Important Safety and Monitoring Information

  • Regular monitoring of liver function
  • Cardiac functions
  • Blood pressure
  • Neurological condition
  • Renal function

Gandhi Medicos: Years of Trusted Excellence in Oncology Care

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