Letrozole
Classification: Anticancer
What is Letrozole?
It is an anticancer medicine, used for hormone-sensitive breast tumors.
Uses of Letrozole
- Breast cancer
- PCOS (off-label)
Working of Letrozole
- It reduces estrogen levels
- Inhibits estrogen-sensitive cancer cell growth and proliferation
Common Side Effects
- Hot flashes
- Muscle pain
- Dizziness
- Night sweating
- Tiredness
Serious Side Effects
- Bone weakening and thinning
- Mood changes
- Severe depression
- Increased risk of fractures
- Increased cholesterol
- Bleeding
Important Monitoring Instructions:
- Liver functions
- Bone density
- Cholesterol levels
- Cognitive functions
- Hormonal levels
Safety Note
- Maintain calcium and vitamin D through supplements
- Avoid alcohol and smoking to prevent bone loss
- Avoid pregnancy during the treatment
Precautions
To be cautiously used in –
- Liver impairment
- Cardiovascular diseases
- High cholesterol
- Risk of thromboembolism
- Weak bones or risk of osteoporosis
Contraindications
- Should not be used in pregnant women and breastfeeding mothers
- Hypersensitivity or allergy to drug components
- Premenopausal women
Warnings
To be used under medical prescription.
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