Maraviroc
Classification: HIV-1 medicine
What is Maraviroc?
It is an anti-retroviral medicine used for HIV-1 infection.
Uses of Maraviroc
- • HIV-1 infections
- • Resistant or intolerant to other anti-retrovirals.
- • CCR5 tropic HIV-1 infection
How does Maraviroc work?
It inhibits the binding of the virus to the receptor. Downregulating its action.
Common Side Effects
- • Cough
- • Fever
- • Flue
- • Dizziness
- • Muscle pain
- • Joint pain
- • Fatigue
- • GIT upset
Serious Side Effects
- • Severe liver toxicity
- • High risk of infections
- • Low blood pressure
- • Irregular heartbeat
- • Coordination issues
- • Mood changes
Precautions of Maraviroc
To be used cautiously in patients with –
- • Liver disorders
- • Heart disorders
- • Kidney dysfunctions
- • Low blood pressure
- • Weak immunity
Contraindications
- • Allergy to the drug
- • Breastfeeding mothers
- • Pregnant women
Warning
- • To be used under medical prescription only
- • It can’t be used as a single treatment for HIV-1.
- • Effective against CCR5-tropic HIV-1 infection only.
Important Monitoring Considerations
Monitor-
- • Liver functions
- • Low blood pressure
- • Increased risk of infections
- • Skin rashes
- • Fever
- • Viral count
- • CD4+ count
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