Mitomycin 10mg Injection

Classification: Anticancer Medicine

Mitomycin?

It is an antibiotic which is used as an anticancer agent against many cancers and tumors.

Uses of Mitomycin

  • • Stomach cancer
  • • Pancreatic cancer
  • • Ovarian cancer
  • • Breast cancer
  • • Uterus cancer
  • • Small cell lung cancer

How does Mitomycin work?

Causes cancer cell death by cross-linking DNA strands of the viral cells.

Common Side Effects

  • • Nausea
  • • Bone marrow suppression
  • • Mouth ulcers
  • • Alopecia
  • • Skin rashes

Serious Side Effects

High doses can lead to:

  • • Anemia
  • • Low platelet count
  • • Lung scarring
  • • Kidney damage
  • • Liver toxicity
  • • Shortness of breath
  • • Fast irregular heartbeat

Precautions

To be cautiously used in patients with:

  • • Pre-existing liver disorder
  • • Kidney disorder
  • • Bleeding disorders
  • • Severe infection
  • • Elderly patients
  • • Myelosuppressant therapy
  • • Respiratory infection
  • • Asthma
  • • Anemia

Contraindications

  • • Not to be used if any previous allergy or hypersensitivity to Mitomycin or any excipients.
  • • Breastfeeding mothers
  • • Pregnant women

Warning

The dose should be monitored and used under supervision.

Important Safety and Monitoring Information

Monitor the following regularly:

  • • Total blood count
  • • Renal functions
  • • Pulmonary functions
  • • Hepatic functions
  • • Necrosis

Storage

Store at 2-8°C, protected from light.

Administration Instructions

  • • To be administered as a slow IV infusion
  • • Avoid IV push or rapid bolus
  • • To be used immediately after reconstitution

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