Mycophenolate Sodium
Classification: Organ Transplant Medicine
What is Mycophenolate Sodium – 500?
Mycophenolate suppresses the immune system and is widely used as post-transplant therapy or for prophylaxis of organ rejection.
Uses of Mycophenolate
- • It is used as prophylaxis for Organ rejection.
- • Kidney transplant
- • Liver transplant
- • Heart transplant
- • Autoimmune diseases – rheumatoid arthritis
How does Mycophenolate work?
It suppresses the B and T immune cells.
Inhibit the immune response to the foreign organ.
Benefits
- • Targeted effect
- • Better tolerance
- • Reduces the need for steroids
- • Reduces the risk of rejection
- • Improves quality of life
- • Supports long-term graft survival
Common Side Effects
- • Skin rashes
- • GIT upset
- • Diarrhea
- • Headache
- • Anemia
- • Infections
- • Stomach pain
- • Hair fall
- • Weakness
Serious Side Effects
- • Bone marrow suppression
- • Gastrointestinal bleeding
- • Renal toxicity
- • Hepatic-toxicity
- • Risk of severe infection
- • Risk of malignancy – leukemia, skin cancer
- • Low platelets – unusual bleeding
Precautions
To be used cautiously in:
- • Kidney impairment
- • Liver disorders
- • Cancers
- • Active infections
- • Elderly patients
- • Safety instructions
- • Maintain contraception during the treatment.
- • Avoid live vaccines (MMR, Varicella) due to a compromised immune system.
Contraindications
- • Pregnant women and breastfeeding mothers
- • Hypersensitivity or allergy to drug components
Warnings
To be used under medical prescription.
Drug Interactions
- • Antivirals
- • Antacids
- • Antibiotics
- • Proton pump inhibitors
- • Other immune suppressants
Important Monitoring Considerations
Monitor for –
- • Total blood count
- • Liver and kidney functions
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