Nintedanib
Classification: Anticancer and Anti-fibrotic
Nintedanib is an oncology medicine that has anti-fibrotic properties and is widely used for various diseases of the lungs and cancers.
Uses:
- • Non-small cell lung cancer
- • Pulmonary fibrosis
- • Systemic sclerosis of the lungs
Working of Nintedanib –
- • It inhibits growth factors
- • It inhibits angiogenesis and fibrosis
Common Side Effects
- • Diarrhea
- • Nausea
- • Vomiting
- • Liver dysfunction
- • Decreased weight
- • Reduced appetite
- • Headache
- • Tiredness
Serious Side Effects
- • Gastrointestinal bleeding
- • Liver toxicity
- • Thromboembolic events
- • High blood pressure
- • Delayed wound healing
- • GIT perforation
Precautions
To be cautiously used in:
- • Severe liver disorders
- • Bleeding disorders
- • Heart disorders
- • Elderly patients
- • Gastrointestinal disorders
- • Before and after surgery
Contraindications
- • Allergy or hypersensitivity to drug components
- • Breastfeeding mothers
- • Pregnant women
Warning
To be used under medical prescription only.
Safety and Monitoring Information
- • Monitor –liver functions, cardiac functions, blood pressure, total blood count
- • Women must use effective contraception while using the medication and for 3 months after the usage.
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