Paclitaxel IP 100 mg
Classification: Anticancer Medicine
What is Paclitaxel IP 100mg?
Paclitaxel is an anticancer medicine that is combined with Human Albumin to enhance its solubility and binding to the blood cells.
It reduces the need for solvents to dissolve paclitaxel.
Uses of Paclitaxel
- • Advanced Stage Breast Cancer
- • Advanced-stage Pancreatic Cancer
- • (Non-small cell) lung cancer
How Does Paclitaxel Work?
- • It binds to the tubulin protein.
- • Arrest the mitotic phase, inhibiting cell division.
- • Stops cancer multiplication and causes cell death.
Common Side-Effects
- • Nausea
- • Vomiting
- • Mouth ulcers
- • Loss of hunger
- • Skin rashes, itchiness
- • Tiredness
- • Hair loss
- • Swelling of the ankles
Toxicities
- • Myelo-suppression
- • Gastrointestinal toxicity
- • Thrombocytopenia
- • Cardiac toxicity
Precaution
To be cautiously used in patients with –
- • Irregular heartbeat
- • Liver disease
- • Low blood count
- • Breathing disorder
Contraindications
Not to be used on people –
- • Allergic to Paclitaxel
- • Breastfeeding women
- • Pregnant women
Warning
To be used under medical supervision, administered slowly over 30 minutes.
Important Safety Information
It should be regularly monitored for –
- • Liver functions
- • Blood count
- • Renal functions
- • Cardiac function
Storage of Paclitaxel Injection
2-8 degrees Celsius storage required and protected from light.
The reconstituted solution is to be used immediately.
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