Palbociclib-125

Composition: Palbociclib – 125

Therapeutic Class: Anti-neoplastic

Palbocib: Globally Validated for Efficacy and Safety

Palbocib is widely prescribed by oncologists and is available worldwide.

Aprazer Healthcare: A Global Pharmaceutical Name

Aprazer, a leading pharmaceutical company manufacturing a range of life-saving medicines in varied therapeutic segments. As the largest oncology medicine exporter, it exports anticancer medicines to 50+ countries. WHO-GMP certified, assured therapeutic efficacy and safety.

What is Palbocib?

It is a targeted therapy drug that is used for:

  • • Hormone-positive (HR+) breast cancer
  • • HER2-negative and advanced-stage breast cancer
  • • It targets genetic mutations of the enzymes like HER2, CDK

Uses of Palbocib

  • • HR+ cancer – hormone receptor-positive breast cancer
  • • HER2-negative breast cancer
  • • Metastatic Breast Cancer

How does it work?

Tyrosine Kinase Inhibitor
It inhibits the crucial enzymes and arrests the stage of the cell cycle, inhibiting cell proliferation.

  • • Stops multiplication
  • • Stops tumor growth

Common Side Effects

  • • Low blood count – low neutrophils, low RBC count
  • • Loss of appetite
  • • Nausea, vomiting
  • • Mouth ulcers
  • • Tiredness
  • • Skin rashes
  • • Hair loss

Serious Side Effects

  • • Severe fall in Neutrophils
  • • Fatal lung inflammation – Pneumonitis
  • • QT prolongation
  • • Elevated liver enzymes
  • • Opportunistic infections – fungal, bacterial

Precautions

To be used cautiously in patients with:

  • • Pre-existing lung disease
  • • Liver dysfunctions
  • • Renal dysfunctions
  • • Blood disorders
  • • Cardiac abnormalities

Contraindication

  • • Not to be used if any previous allergy or hypersensitivity to Palbociclib or any excipients
  • • Breastfeeding mothers
  • • Pregnant women

Warning

To be used under medical prescription only.

Important Safety and Monitoring Information

Regular monitoring of the:

  • • Liver function – Elevated liver enzymes
  • • Blood count – CBC count
  • • Respiratory functions – interstitial lung disease
  • • Cardiac functions – QT prolongation
  • • Opportunistic infections – fungal, bacterial