Remdesivir 100mg

Classification – Antiviral Medicine

What is Remdesivir?

It is an antiviral medicine used against COVID-19.

Uses –

  • • Treatment of Coronavirus disease – COVID-19

Benefits –

  • • Reduces viral replication
  • • Shortens recovery time
  • • Delays disease progression
  • • Reduces the need for ventilation

Working of Remdesivir

Inhibits viral replication
Slows or stops the viral growth

Common side effects

  • • Headache
  • • Nausea
  • • Skin ulcers
  • • Liver impairment
  • • Low blood pressure
  • • Pain, swelling,
  • • Irritation at the site of injection

Serious side effects

  • • Hepatotoxicity
  • • Allergy
  • • Bradycardia
  • • Kidney impairment

Precautions –

To be used cautiously in:

  • • Liver disorders
  • • Renal disorders
  • • Heart dysfunctions
  • • Children
  • • Breastfeeding women
  • • Pregnant women

Contraindications

Not to be used in patients-

  • • Hypersensitivity or allergy to drug components
  • • Severe liver impairment
  • • Severe hepatic disorder

Warnings

Prescription drug to be used under medical supervision.

Drug Interactions

  • • Nephrology medicines
  • • Rifampin
  • • Phenytoin
  • • Carbamazepine
  • • Methotrexate
  • • Isoniazid
  • • Azoles
  • • Hydroxychloroquine

Important safety and monitoring information

  • • Blood pressure
  • • Liver functions
  • • ECG, cardiac functions
  • • Regular monitoring of electrolytes

Storage:

To be stored at 2-8 degrees Celsius
Protect from light

Administration instructions

Slow IV administration over 30–120 minutes and monitor for hypotension, nausea, chill, and fever.

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