Lapatinib

Lapatinib

• Classification - Anticancer Medicine

What is Lapatinib?

It is an anticancer medicine that works against hormone-sensitive breast cancer.

Uses of Lapatinib

• HER-2 positive breast cancer
• Hormone-sensitive breast cancer

How does Lapatinib work?

• Stops cancer multiplication and growth.
• Shrinks the tumor.

Common side effects

• Diarrhea
• Nausea
• Skin rashes
• Reduced appetite
• Hand-foot syndrome
• Liver dysfunction
• Heart dysfunction

Serious side effects

• Severe diarrhea
• Dehydration
• Liver toxicity
• Shortness of breath
• Decreased heart function
• Symptoms worsen due to tumor changes

Precautions

• To be cautiously used in -
• Liver disorders
• Heart disorders
• Lung disease
• People prone to dehydration
• Caution when used with other drugs like ketoconazole, phenytoin
• Elderly

Contraindications

• Should not be used in pregnant women and breastfeeding mothers.
• Hypersensitivity or allergy to drug components.

Warnings

• To be used under medical prescription.

Safety instructions

Maintain contraception during the treatment.

Avoid live vaccines (MMR, Varicella) due to a compromised immune system.

Important Monitoring Considerations

• Monitor for-
• Liver functions
• Heart functions
• Hydration status
• Electrolyte balance

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