Ivermectin

Ivermectin

• Classification - parasite infection medicine

Ivermectin?

It is a medicine used to kill parasites or worms and is widely used in parasitic infections.

It is WHO's recommended essential medicine.

Uses of Ivermectin-

• Used against parasitic infections-
• Filarial worms
• River blindness
• Scabies
• Head lice
• Hook-worm infection

Working of Ivermectin

• It causes paralysis of the parasite
• Kills parasites

Benefits

• It has a broad spectrum of activity, used against many parasites.
• Useful in community treatment initiatives.
• Well tolerated
• Repeated doses are safe.

Common side effects

• Headache
• Dizziness
• Muscle pain
• Diarrhea
• Skin rashes
• Fever

Serious side effects

• Peeling of the skin
• Severely low blood pressure
• Seizures
• Mental confusion
• Inflammation in the brain

Precautions -

• To be cautiously used in -
• Psychiatric disorders- seizures, depression
• Severe liver disorder
• Pregnant and breastfeeding women
• High parasitic burden
• Elderly patients
• With CNS depressant drugs

Contraindications

• Allergy to Ivermectin
• Meningitis
• 1st trimester of pregnancy
• Severe liver impairment
• Children weighing less than 15kg or under 5 years of age
• Concomitant infections

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