Imatinib
Imatinib Mesylate
- Classification: Anticancer
Imatinib Mesylate?
It is a targeted anticancer treatment used against various blood cancers and bone marrow cancers.
Uses of Imatinib
- Chronic myeloid leukemia
- Myeloproliferative disease
- Lymphoblastic leukemia
- Gastrointestinal tumors
- Philadelphia Chromosome-Positive leukemia
How does Imatinib work?
- It blocks cell multiplication and division.
- Blocks rapidly dividing cells.
Common side-effects
- Fluid retention
- Skin rash
- Headache
- Indigestion- nausea, diarrhea
- Abdominal pain
- Loss of appetite
- Muscle pain, joint pain
- Anemia
Serious side effects
- Hepatic-toxicity - jaundice, hepatitis
- Heart issues- irregular heartbeat, arrhythmias
- Shortness of breath
- Bone marrow suppression
- Perforation in the gastrointestinal wall
- Severe rash or peeling of the skin
Precautions:
- To be used cautiously in patients with -
- Kidney disorders
- Liver disorders
- Cardiac insufficiencies
- Thyroid disease
Contraindications
- Allergy or hypersensitivity to Imatinib or its components.
- Breastfeeding mothers
- Pregnant women
- Congestive heart failure
Important safety and monitoring information
- Regularly monitor-
- Liver functions
- Blood count
- Weight and swelling in the body
- Pleural/pericardial effusion or pulmonary edema
- Cardiac functions - ECG/ECHO
- Thyroid functions -TSH/T4 Levels
Important Drug Interactions
- Monitor closely or consider dose reduction when co-administered with-
- Antifungals, macrolides, warfarin, statins, and rifampin-like drugs.
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Formulations based on "Imatinib" (6)
Imat 400 Tablet
Imatinib mesylate
Zydus Healthcare manufactures Imat 400 mg tablet.
Imatikast Tablet 400mg
Imatinib
It is a targeted therapy anticancer drug used for various cancers of the blood, bone marrow, and various types of tumors.
Imatib 100mg Tablet
Imatinib mesylate
Imatib 100 Tablet has a wide range of cancer treatments available. Blood malignancies (such as chronic myeloid leukemia and acute lymphocytic leukemia) and stromal tumors of the gastrointestinal tr...
Veenat 100
Imatinib
It is a type of drug known as a tyrosine kinase inhibitor. It is being used to treat blood malignancies such as chronic myeloid leukemia, acute lymphocytic leukemia, and gastrointestinal stromal tu...
Imatikast (Imatinib 100 mg)
Imatinib
Imatinib 100 mg tablet treats specific types of acute cancers like gastrointestinal stromal tumors, chronic myeloid leukemia, myeloproliferative disease, lymphoblastic leukemia, etc. This medicatio...
Veenat 400 Tablet
Imatinib
Veenat 400 (Imatinib), the indigenous drug, is used for patients with different types of blood cancer caused due to irregular growth of white blood cells (WBCs). It hinders the growth of these abno...