Ribavirin

Ribavirin

• Classification: Hepatitis C medicines

What is Ribavirin?

Its antiviral nature is used against Hepatitis C treatment.

Uses of Ribavirin

• Chronic Hepatitis C
• Respiratory Viral Disease

Working of Ribavirin

• It changes the viral cell integrity.
• Inhibits both RNA and DNA multiplication and replication.

Benefits

• It can be used in combination with other antivirals.
• Boost the effectiveness of other antivirals.
• Lowers the risk of relapse
• Effective against various viral RNA /DNA
• Can be used for Respiratory viruses in infants and immunocompromised individuals

Common Side Effects

• Nausea,
• Dizziness,
• Headache,
• Digestive issues,
• Tiredness,
• Diarrhea.

Serious Side Effects

• Destroying red blood cells causes severe Anemia.
• Pancreatitis
• Hepatic toxicity- Avoid alcohol while treatment
• Neuropsychiatric condition- depression, confusion
• Cardiac toxicity - heart attack, strokes
• Suppresses the immune system

Precautions

• To be cautiously used in patients with -
• Liver disorders
• Kidney disorder
• Anemic
• Severe psychiatric illness
• Autoimmune disease
• Severe heart disease
• And co-administration with another drug like zivoduvine.

Contraindications

• Allergy or hypersensitivity to any drug component.
• Breastfeeding mothers
• Pregnant women

Warning

Take only when recommended by the doctor.

Important Safety and Monitoring Information

• Regular monitoring of -
• Hepatic functions,
• Renal functions,
• Cardiac functions,
• Co-infections, and neuropsychiatric adverse reactions.
• Drug interactions -
• Zidovudin, Didanosine, Azathioprin -
• It increases the risk of a fall in RBC count and lactic acidosis.
• Antacids - They may impair antacid absorption.

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