Description
Leucokast 50 Injection
Composition – Leucovorin Calcium Injection IP (50mg /5ml)
Classification – Folic Acid Derivative
What is Leucokast 50 Injection?
Leucokast 50 mg injection is a leucovorin injection manufactured by Aprazer Healthcare.
It is widely used as a cancer supportive treatment.
Leucokast (leucovorin injection) is used to rescue healthy cells after anticancer treatment.
It is used in anticancer therapies that interrupt the folic acid synthesis in the body.
Aprazer Healthcare – The Largest Oncology Injectable Manufacturer
Aprazer Healthcare is the leading anticancer drug manufacturer in India.
It manufactures global standard anticancer drugs.
Aprazer Healthcare is the largest anticancer injection exporter to countries worldwide.
It manufactures the largest range of anticancer injections.
• Leucokast 50 – Leucovorin injection
• Carbokast 150 – Carboplatin injection
• Daunozer 20 – Daunorubicin Injection
• Nab Paclikast 100 – Paclikast injection
What Are Leucokast 50 (Leucovorin Injection) Uses?
It is widely used as a folic acid rescue therapy.
It is used to recover normal body cells after-
• Methotrexate therapy
• Trimethoprim and methotrexate therapy
It is used as an adjuvant to (5-FU). It enhances its effects.
How Does Leucokast 50 (Leucovorin Injection) Work?
Folic Acid Rescue Agent –
• The anticancer therapy depletes the folic acid synthesis.
• The leucovorin injection is a folic acid derivative.
• It recovers the folic acid levels in the body.
• Folic acid is essential for cell growth.
Adjuvant to Fluorouracil Drugs –
• It enhances the chemotherapy effect.
• It prolongs the action of fluorouracil (5-FU) drugs.
• 5–FU compounds can bind strongly to the enzyme.
• It inhibits cancer cell synthesis.
What Are Leucokast (Leucovorin Injection) Side Effects?
Gastrointestinal side effects include-
• Nausea
• Tiredness
• Vomiting
• Mouth sores
• Skin rashes
• Hair loss
How Does Leucokast (Leucovorin Injection) Lead to Severe Side Effects?
It is used with Fluorouracil compounds. It can cause toxic effects.
It can cause a reaction (allergy).
• Flu-like symptoms
• Severe skin allergy
• Rashes and itchiness
• Swelling in the face
It can cause CNS side effects-
• Fainting
• Seizures
• Confusion
Warnings for the Use of Leucokast (Leucovorin Injection)-
It should be used under a doctor’s supervision.
It is prescription medicine.
Not to be used as a folate supplement.
It must not be injected into the spine.
Not to be used if any previous allergy
It should not be used for anemia.
It must be avoided in breastfeeding mothers.
What Drugs Cannot Be Given With Leucokast (Leucovorin Injection)?
It can show serious drug interactions.
It can lead to toxicity.
It should not be given with –
• Anti-seizure drugs
• Supplements
• Vitamins
• Certain anticancer medicines
Who Should Not Use Leucokast (Leucovorin Injection)?
Avoid in people with vitamin B-12 deficiency.
To be used carefully in conditions like-
• Epilepsy
• Kidney disorders
• Liver disorders
• Bleeding disorders
• Gastrointestinal disorder
It requires regular monitoring of –
• Blood cell count
• Liver functions
• Electrolyte balance
• Calcium levels
• Vitamin B-12 levels
How to Store and Use Leucokast (Leucovorin Injection)?
The injection needs to be stored at low temperatures.
The injection is to be kept at 2-8 degrees Celsius.
Do not freeze the injection.
Keep away from light.
To be used as IV and IM.
Use the solution (diluted) immediately.
Why is Gandhi Medicos a Reliable Pharmaceutical Drug Supplier?
Gandhi Medicos is the leading drug supplier, wholesaler, and the top drug distributor.
We outsource quality medicines from the leading brands.
Gandhi Medicos is a top online pharmacy.
Partnering with the leading pharmaceutical manufacturers, we outsource original medicines.
We bring the advanced treatment drugs accessible to all.
Outsourcing the best quality anticancer medicines, Gandhi Medicos is a leading supplier of anticancer medicines.
We supply bulk anticancer medicines globally.



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