Abirakast 500mg Tablet
Molecular Salt: Abiraterone Acetate
Composition: Abiraterone Acetate IP - 500mg
Classification - Anticancer Medicine
What is Abirakast?
It is an anticancer medicine that blocks the androgen receptor and is used against resistant prostate cancers.
Uses of Abirakast
Metastatic Castration Resistant Prostate Cancer
Metastatic Castration sensitive Prostate cancer
How does Abirakst work?
It inhibits testosterone-receptor binding, shrinks tumor size, and proliferation of cancer cells.
Common Side Effects of Abirakast
Hypokalemia
Hypertension
Liver dysfunction
Weakness
Fluid retention and swelling
Joint pain, muscle pain
UTI
Fractures
Serious Side-Effects
Cardiac abnormalities - Arrhythmia, irregular heartbeat
Hepatic-toxicity - yellowing of eyes, jaundice
Adrenal insufficiency- severely low potassium
Hypertensive Crises - Severely elevated blood pressure
Osteoporosis- severe bone loss
Contraindications
Not to be used in patients-
Hypersensitivity or allergic reaction to the drug or its excipients.
Abirakast is not recommended for use in women.
Breastfeeding mothers
Pregnant women
Precautions
To be used cautiously in patients with -
Cardiac abnormalities
Hepatic impaired functions
Renal impaired functions
Warnings
Prescription drug to be used under medical supervision.
Important safety and monitoring information
Abirakast requires regular monitoring for
Hematological functions- blood count
Blood pressure
Liver functions
ECG, cardiac functions
Regular monitoring of electrolytes
Note \- To reduce mineralocorticoid side-effects, it is generally co-administered with prednisolone.
It must be taken on an empty stomach.
Maintain effective contraception during the treatment
Aprazer Healthcare
Tablet (500 mg)
60 Tablets
Store below 30°C
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