Cytarzer

Composition: Cytarabine 1000mg

Therapeutic class: Antimetabolite, Antineoplastic

What is Cytarzer?

It is an anticancer medicine used in various types blood cancers and solid tumors.

Uses of Cytarzer

Advanced stage Acute Myeloid Leukemia (AML).

Leukemia of the meninges

Lymphocytic/ No lymphocytic leukemia

Refractory leukemia

How does it work?

It mimics DNA bases, inhibits DNA replication, and terminates the chain, causing cell death.

Common side effects

Hair loss

Skin rashes

Liver dysfunctions

Mouth sores

Weakness

Indigestion

Anemia

Neutropenia

Serious side effects

Dose-dependent side effects -fever, pain, muscle pain

Neurological dysfunction -confusion, blurring of speech

Pulmonary embolism and fibrosis

Irritation of the eye, conjunctivitis.

Bleeding risk

Liver toxicity

Precautions

To be used cautiously in patients with -

Liver dysfunction

Renal dysfunction

Immune-compromised patients

Neurological disorders

Contraindications

Not to be used if any previous allergy or hypersensitivity to Cytarabine or any excipients.

Breastfeeding mothers

Pregnant women

Warnings

To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.

Important safety and monitoring information

Monitor blood count and hepatic and neurological assessments regularly, manage infection risks, and assess ocular and renal functions.

Storage

It should be stored at 2-8 degrees Celsius, protected from light.

Administration Instructions

To be administered intrathecal, subcutaneous, or as a slow IV infusion.

To be used immediately after reconstitution.

Cytarzer 1000mg