Cytarzer-100mg Injection

CYTARZER 100MG

Composition - Cytarabine IP 100 mg

Classification - Anticancer Medicine

What is Cytarzer 100mg?

Cytarzer is an anticancer medicine used for various cancers of the blood.

Uses

• Acute Myeloid Leukemia
• Acute promyelocytic leukemia induction
• Acute Lymphocytic Leukemia
• Chronic Myeloid Leukemia
• Non-Hodgkin Lymphoma
• Meningeal Leukemia

How does Cytarzer work?

It inhibits DNA enzymes (polymerases).

Inhibit DNA elongation and replication.

Inhibiting cell division causes cell death.

Contraindication -

Hypersensitivity or allergy to drug components.

Cannot be used in Active Meningeal Infections.

Pregnant women

Breastfeeding women

Toxicities

• Myelosuppression
• High doses cause corneal toxicity
• Cerebral and cerebellar toxicity

Common side-effects -

Irritation at the administration site, gastrointestinal disturbances, stomatitis, conjunctivitis, reversible hepatic enzyme elevation, mouth sores, and dermatitis.

Severe Side Effect-

Myelosuppression- decreased overall blood count.

Warnings

To be used as prescribed by the doctor.

Important safety and monitoring information

Regularly Monitor -

Blood count

Hepatic functions

Neurological assessments

Infection risks,

Ocular functions

Renal functions.

Storage

Keep at 2-8 degrees Celsius, protect from light.

Administration Instructions

To be administered intrathecal, subcutaneous, or as a slow IV infusion.

To be used immediately after reconstitution.

Important handling instructions

It should be handled wearing gloves, since it's toxic.

The metallic needles, aluminum syringes degrade drug potency.