Dacarzer-200 Injection
Molecular Salt: Dacarbazine (200mg)
Composition- Dacarbazine -200mg
Classification - Anticancer Medicine
What is Dacarzer?
It is a cytotoxic anticancer that is used to treat cancers of the lymph and the skin.
Uses of Dacarzer -
Skin cancer
Hodgkin lymphoma
Tissue sarcoma
Brain tumors
Breast cancer
Lung cancer
How does Dacarzer work?
It inhibits DNA replication and synthesis.
Causes Cancer cell death
Contraindications:
It should be used cautiously in patients who have had hypersensitivity in the past or people having hepatic and renal insufficiency.
Pregnant and breastfeeding women.
Toxicities:
Myelosuppression (Bone Marrow Suppression)
Hepato-toxicity
Secondary malignancies
Local tissue necrosis
Precautions:
Renal and hepatic compromised patients.
Immune dysfunctions
Bone marrow disorders
Bleeding disorders
Pre-existing GIT disorders
Common side effects:
Nausea and vomiting
Reduced appetite
High risk of infection
Bruising and bleeding
Anemia (low red blood cell count)
Photosensitivity
Warning:
To be used under the supervision of a medical practitioner or an oncology care specialist.
Dacarbazine given intravenously may sometimes leak outside the vein, causing pain, tissue damage, local bruising, and flare.
Storage
It should be stored at 2-8 degrees Celsius, protected from light.
Administration Instructions
To be administered as a slow IV infusion.
To be used immediately after reconstitution.
Important Monitoring Instructions -
Regularly monitor -
Blood count
Liver functions
Kidney functions
Early signs of infections
Necrosis and vein leakage
Hydration status
Aprazer Healthcare
Injection (200mg)
1.0 Powder for Injection in 1 vial
Store below 30°C
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Storage Warning: Biological injectables, biosimilars, and active oncology agents are flagged as temperature-sensitive cargo and are packed strictly inside thermal containers coupled with real-time digital temperature tags.