Dacarzer-200 Injection

Dacarzer-200 Injection

Composition- Dacarbazine -200mg

Classification - Anticancer Medicine

What is Dacarzer?

It is a cytotoxic anticancer that is used to treat cancers of the lymph and the skin.

Uses of Dacarzer -

Skin cancer

Hodgkin lymphoma

Tissue sarcoma

Brain tumors

Breast cancer

Lung cancer

How does Dacarzer work?

It inhibits DNA replication and synthesis.

Causes Cancer cell death

Contraindications:

It should be used cautiously in patients who have had hypersensitivity in the past or people having hepatic and renal insufficiency.

Pregnant and breastfeeding women.

Toxicities:

Myelosuppression (Bone Marrow Suppression)

Hepato-toxicity

Secondary malignancies

Local tissue necrosis

Precautions:

Renal and hepatic compromised patients.

Immune dysfunctions

Bone marrow disorders

Bleeding disorders

Pre-existing GIT disorders

Common side effects:

• Nausea and vomiting
• Reduced appetite
• High risk of infection
• Bruising and bleeding
• Anemia (low red blood cell count)
• Photosensitivity

Warning:

To be used under the supervision of a medical practitioner or an oncology care specialist.

Dacarbazine given intravenously may sometimes leak outside the vein, causing pain, tissue damage, local bruising, and flare.

Storage

It should be stored at 2-8 degrees Celsius, protected from light.

Administration Instructions

To be administered as a slow IV infusion.

To be used immediately after reconstitution.

Important Monitoring Instructions -

Regularly monitor -

Blood count

Liver functions

Kidney functions

Early signs of infections

Necrosis and vein leakage

Hydration status