Dorucin 10mg

Dorucin 10 mg

Composition - Doxorubicin Hydrochloride 10 mg

Therapeutic Class – Chemotherapeutic drug

What is Dorucin?

Dorucin is an anti cancer medicine that is used as a cytotoxic agent to kill viable cancer cells for various types of cancer.

Uses of Dorucin-

• Blood cancers
• Leukemia
• Lymphocytic cancers
• Breast cancer
• Lung cancer
• Sarcomas
• Ovarian cancers

How does Dorucin work?

• Blocks the enzyme topoisomerase 2
• Inhibit cancer cell division and growth
• Causes cancer cell death

Common Side Effects of Dorucin

• GIT upset – Nausea, vomiting
• Mouth and throat ulcers
• Hair loss
• Urine discoloration
• Red eyes.

Serious Side-Effects

• Difficulty in breathing
• Skin rash
• Seizures
• Red blood in stool and vomit

Toxicities

• Dorucin causes dose-dependent toxicities
• Cardio toxicity – Arrhythmia, irreversible cardiac failure
• Myelosuppression – decreases in red blood cell count, white blood cells, and platelets.
• Vesicant effect – severe local tissue necrosis

Contraindications

• Not to be used in patients with prior hypersensitivity to the drug or its excipients.
• Breastfeeding mothers
• Pregnant women

Precautions

To be used cautiously in patients with

• Heart disease
• Low blood count
• Liver disease

Warnings

To be used under medical supervision, given as a slow intravenous infusion over 15-60 minutes.

Important Safety and Monitoring Considerations

Regular monitoring of the liver function, cardiac function, and regular blood count is required.

Storage:

Store at 2-8°C (refrigerator), protected from light.

Reconstituted solution to be used immediately.