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Geftinat
| Product Name | Geftinat |
| Dose/Strength | 250 mg |
| Packaging Size | 30 Tablets |
| Brand |
|---|
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Description
Geftinat 250 mg (Gefitinib) is specified against a type of lung cancer (non-small cell) wherein cells are mutated in epidermal growth factor receptor (EGFR). EGFR is expressed on the cell surface of these cancerous cells. Geftinat 250 mg (Gefitinib) selectively targets the proteins that are mutated in these cells. It is taken orally as a 250 mg dose once daily with or without food.
Additional properties of Geftinat 250 mg (Gefitinib):
Once Geftinat 250 mg (Gefitinib) enters our system, it takes around 3 to 7 hours for absorbing at least 60% of the drug. With 90% binding affinity with cancerous cells, Gefitinib carries out anti-cancer activities by metabolizing in the liver. Finally, more than 50% of the drug gets excreted out of the system within 2 days.
Modifications in dosing based on the side-effects:
| Type of modification | Disease condition | Side-effects |
| Hold back Geftinat 250 mg (Gefitinib) for 14 days | Worsened respiratory problems | Fever, shortness of breath and cough |
| Worsening liver functions | Jaundice (yellow-coloured skin or eyes), dark-coloured urine, loss of appetite, abdominal pain | |
| Diarrhea for up to 14 days | Severe and persistent diarrhea | |
| Keratitis or other severe disorders of the eyes | Watery eyes, light sensitivity, blurred vision, eye pain, red-eye, or changes in the vision | |
| Skin disorders (Bullous & exfoliative) | Redness of skin, rashes, acne, and itching | |
| Permanently stop Geftinat 250 mg (Gefitinib) | Interstitial Lung Disease (ILD) | Lung infiltration, pneumonitis, acute respiratory distress syndrome, or pulmonary fibrosis |
| Severe problems in the liver (Hepatic impairment) | Jaundice (yellow coloured skin or eyes), dark coloured urine, loss of appetite, severe abdominal pain | |
| Tear in the stomach or intestinal wall (Gastrointestinal perforation) | Severe pain in the abdomen, Vomit blood, red or black coloured stools | |
| Inflammation of the eyes (Persistent ulcerative keratitis) | Watery eyes, light sensitivity, blurred vision, pain in the eyes, red-eye, or changes in the vision | |
| Embryo-fetal toxicity | – |
Note: Patients can resume Gefitinib after the side-effects vanish.
Other warnings before taking Gefitinib:
The healthcare provider should be notified regarding,
- Lung or breathing problems
- Liver complications
- Difficulties in visualizing
- Pregnancy
- Breastfeeding
- Proton pump inhibitors, antacids or other medicines
Most common side-effects:
- Diarrhea
- Skin reactions (rashes, dry skin and itching)
- Sickness
- Ulcers on the mouth
- Loss of appetite
Note: These are not all side-effects of Gefitinib, inform your healthcare provider if you witness others.
Reviews (12)
12 reviews for Geftinat
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All Trademarks, Brands and Service marks that appear on this website belong to their respective owner.
If you think you may have a medical emergency, call your doctor or go to the emergency department, or immediately. Gandhi Medicos does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on Gandhi Medicos. Reliance on any information provided by Gandhi Medicos, Gandhi Medicos employees, contracted writers, or medical professionals presenting content for publication to Gandhi Medicos is solely at your own risk.
The Site may contain health- or medical-related materials or discussions regarding sexually explicit disease states. If you find these materials offensive, you may not want to use our Site. The Site and its Content are provided on an "as is" basis.
Links to educational content not created by Gandhi Medicos are taken at your own risk. Gandhi Medicos is not responsible for the claims of external websites and education companies.
General Advisory:We advise you to stick to medication routine (or medication adherence), i.e. to take medications as prescribed – the right dose, at the right time, in the right way and frequency. Not taking medicines as prescribed by a doctor or instructed by a pharmacist could lead to disease getting worse, hospitalization, even death.
All Trademarks, Brands and Service marks that appear on this website belong to their respective owner.
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