L-Aprakast 10000 IU
Molecular Salt: L Asparaginase Injection 10000 Iu
L-Aprakast
Composition: L Asparaginase 10000 IU for IM and IV administration
Therapeutic Class – Antineoplastic agent
What is L-Aprakast?
L-Aprakast is an enzyme used as an anticancer medicine that blocks the cancer processes of growth and division.
It is the targeted therapy drug that kills the viable cells without harming the normal cells
It is used to achieve complete remission in adults and pediatric patients.
Uses of L-Aprakast –
- Lymphoblastic Leukemia (acute)
- Lymphoblastic lymphoma
How does L-Aprakast Work?
- Break down the L-asparagine enzyme
- Cancer cell starvation
- Apoptosis and cell death
Common Side Effects of L-Aparakast
- Increases infection risks
- Blood clots
- Diarrhea
- Weight loss
- Loss of appetite
- High albumun levels, bilirubin levels
- Oedema
- Lowered blood pressure
- Abdominal pain
Serious Side-Effects
- Pancreatic bleeding
- Thromboembolism- clots and strokes
- Bone marrow suppression – thrombocytopenia
- Shortness of breath
Toxicities
- Hepatotoxicity
- Thrombosis and bleeding
- Pancreatitis
Contraindications
- Not to be used in patients with prior hypersensitivity to the drug or its excipients.
- Breastfeeding mothers
- Pregnant women
Precautions
To be used cautiously in patients with
- Heart disease
- Low blood count
- Liver disease
- Pancreatitis
Warnings
To be used under medical supervision only, do not mix dextrose-containing solutions.
Important safety and monitoring information
Regular monitoring is required for liver functions, pancreatic enzymes, blood coagulants, and sugar levels.
Storage:
Store at 2-8 degrees Celsius (refrigerator), protected from light.
Reconstituted solution to be used immediately.
Aprazer Healthcare
Injection (10000 Iu)
Single Pack Unit
Store below 30°C
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Storage Warning: Biological injectables, biosimilars, and active oncology agents are flagged as temperature-sensitive cargo and are packed strictly inside thermal containers coupled with real-time digital temperature tags.