Lenvakast 4 mg (Lenvatinib) is the anti-cancer agent employed for managing different types of cancer. Lenvakast 4 mg (Lenvatinib) is indicated against Hepatocellular Carcinoma (HCC), Renal Cell Carcinoma (RCC) and Differentiated Thyroid Cancer (DTC). Lenvakast 4 mg (Lenvatinib) is primarily taken at the same time every day, however, the dosing differs based on the type of cancer. The drug is consumed orally either with or without food.
The table below shows different dosing patterns of Lenvakast 4 mg (Lenvatinib) based on the type of cancer and conditions associated with it.
Table: Administration of Lenvakast 4 mg (Lenvatinib):
Type of cancer | Recommended dosage | Number of Tablets | Associated condition |
HCC (Liver cancer) | Body weight: ≥60 kgs: 12 mg | 3 tablets of 4 mg | When surgery is not an option. |
Body weight: <60 kgs: 8 mg | 2 tablets of 4 mg | ||
RCC (Kidney cancer) | 18 mg plus 5 mg everolimus | 1 tablet of 10 mg
2 tablets of 4 mg |
– |
DTC (Cancer in the thyroid glands) | 24 mg | 1 tablet of 4 mg 2 tablets of 10 mg |
When patients cannot undergo radioactive iodine therapy |
Clinically, Lenvakast 4 mg (Lenvatinib) is an inhibitor drug which stops growth, proliferation and aggravation of cancer by rendering adept anti-tumor activities. It takes around 1 to 4 hours to completely absorb in the system. Subsequently, it binds very efficiently (98% to 99% of binding efficacy) with cancer cells to carry its anti-tumor actions. Once the actions are done, it takes around 28 hours to eliminate 50% of the drug from the system.
Warnings and Precautions associated with Lenvakast 4 mg (Lenvatinib):
The healthcare provider should be informed about certain conditions before administering Lenvakast 4 mg (Lenvatinib). The conditions include,
- High blood pressure (Hypertension)
- Heart problems
- History of blood clots, stroke, heart attack, or changes in vision
- Kidney or liver complications
- Tear in the stomach or intestines (Perforation)
- Atypical connections between two sections of the gastrointestinal tract (Fistula)
- Low levels of calcium in the blood (Hypocalcemia)
- Severe bleeding through different regions of the body
- Problems in healing the wounds
- Increased amounts of protein in the urine (Proteinuria)
Side-effects associated with Lenvakast 4 mg (Lenvatinib):
Diarrhea is the most common side-effect of the drug. However, there are certain common side-effects of Lenvakast 4 mg (Lenvatinib) based on the type of cancer. Among them, tiredness, vomiting, nausea, pain in the stomach region (abdomen), joints and muscles, loss of weight and appetite, are the most common ones in all three types of cancers.
HCC (Liver cancer) | RCC (Kidney cancer) | DTC (Cancer in the thyroid glands) |
Rashes | Mouth sores | Mouth sores |
Redness | Swelling on arms and legs | Headache |
Itching or peeling of your skin | Cough | Hoarseness |
Bleeding | Difficulty in breathing (Dyspnea) | Rashes |
Hoarseness | Rashes | Redness |
Change in levels of thyroid hormones | Bleeding | Itching or peeling of your skin |
Note: Lenvakast 4 mg (Lenvatinib) might show other side-effects as well. Refer your healthcare provider for more updates regarding the drug.
Lenvakast 4 mg (Lenvatinib) is also available in these countries: (South East Asia, South America, Eastern Europe, Bulgaria, Croatia, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Macedonia, Poland, Republic of Kosovo, Republic of Moldova, Romania, Russia, Serbia, Slovak Republic and Slovenia.)
FAQs for Lenvakast 4mg
Lenvakast 4 mg is a strong medicine used to treat advanced or progressive thyroid cancer in adults when the radiation treatment fails to stop cancer’s growth. It consists of a very active substance called Lenvatinib.
Apart from treating thyroid cancer, a few other diseases can be treated using this medicine, like hepatocellular carcinoma or liver cancer, if no other anti-cancer medicines traveled through the adult’s bloodstream before.
Lenvakast medicines block the action of receptor tyrosine kinases, which are a kind of protein. RTK is responsible for developing blood vessels that carry nutrients and oxygen to different cells and help in their nourishment.
Lenvakast is made up of the active substance Lenvatinib.
Some of the other ingredients present in Lenvakast other than the active substance are Hydroxypropyl Cellulose, low-substituted Hydroxypropyl Cellulose, Microcrystalline Cellulose, Mannitol, Talc, and Calcium Carbonate.
The shell contains Red Iron Oxide, Titanium Dioxide, Yellow Iron Oxide, and Hypromellose.
The print’s ink on the capsule shell consists of Potassium Hydroxide, Shellac, Propylene Glycol, and Black Iron Oxide.
Some of the precautions that you must consider are:
- Ignore using if you have any allergic reaction consuming Lenvatinib or any other components mentioned above
- If you are lactating
Before continuing Lenvakast, your doctor should know certain things about your health like:
- Whether you had any surgery or radioactive therapy
- Your age
- High BP
- Any persisting liver or kidney problems
Before being prescribed Lenvakast, your doctor essentially should carry out some tests to determine whether you will be eligible to take medicine.
They might also advise you to take care according to your medical conditions and the side effects you might face.
Lenvakast is specifically not recommended for children and those who are in their adolescence. The results of the medicine on younger people are still unknown.
Those who are pregnant or lactating should inform their doctor before they take it. The interaction with your ongoing drugs may have some reaction with this medicine.
Consuming the drug during pregnancy is very harmful to your baby.
While breastfeeding, the medicine should also not be taken since the components may pass through the breast milk to the baby.
Consumption may have certain side effects on your body.
They include feeling weak or numb, severe headaches, confusion, seizure, changes in vision or dizzy feeling, or difficulty in taking. In this case, the patient should consult the doctor.
If the patient feels pains in the chest, arms, back, or neck, the patient might have heart problems. It also causes irregularity in heart rate, shortness of breath, continuous coughing, etc.
If Lenvakast causes internal bleeding, black or bloody stools, or coughing up blood are its symptoms.
The medicine should be stored in a cool place, not above 25 degrees Celsius.
Generally, you should take one per day but act according to your doctor’s recommendation.
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John Smith –
Lenvakast 4 mg (Lenvatinib) is the very effective medicine for the treatment of kidney cancer.
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For the past two months, I’ve been on Lenvatinib. I noticed a substantial improvement in my health.
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Best medicine for the Renal Cell Carcinoma (kidney Cancer).
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