Paclikast 260 mg

Paclikast -260 mg

Composition: Paclitaxel -260 mg

Therapeutic class: Anti-neoplastic

What is Paclikast?

It is a chemotherapy anti-cancer medicine, used against various cancers and solid tumors.

Uses of Paclikast

Breast cancer

Ovarian cancer

AIDS related sarcoma

Non-small cell lung cancer

Pancreatic cancer

Head and neck cancer

How does it work?

It inhibits the double-stranded DNA breakage to single-strand, inhibits the replication and multiplication of DNA.

Common side effects

Tiredness

Hair loss

Increases the risk of infections

Indigestion - diarrhea, constipation

Hypotension

Mouth ulcers

Muscle and joint pain

UTI

Anemia

Numbness of limbs, tingling in hands, fingers

Serious side effects

Bone Marrow Suppression

Slow heartbeat

Shortness of breath

Blood clot

Chest pain

Liver toxicity

Local tissue injury

Pain in the abdomen

Precautions

To be used cautiously in patients with -

Liver disorders

Renal disorders

Hypertension patients

Elderly patients

Pre-existing infections

Immune-compromised patients

Adjuvant to myelosuppressive treatments

Contraindications

Not to be used if any previous allergy or hypersensitivity to Paclitaxel or any excipients.

Breastfeeding mothers

Pregnant women

Warnings

To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.

Important safety and monitoring information

Regularly monitor blood count, hepatic, manage infection risks, cardiac functions, and early signs of peripheral neuropathy.

Storage

It should be stored at 2-8 degrees Celsius, protected from light.

Administration Instructions

To be administered as a slow IV infusion only.

Do not give as an IV push/bolus.

To be used immediately after reconstitution.