Palbocib-125

Palbocib-125

Composition - Plabociclib - 125mg

Classification - Anticancer Medicine

What is Palbocib?

It is a targeted therapy drug that is widely used against breast cancer.

Uses of Palbocib-

HR+ cancer - hormone receptor-positive breast cancer

HER2-negative breast cancer

Metastatic Breast Cancer

How does Palbocib work?

Tyrosine Kinase Inhibitor

It inhibits the cell cycle

Stop multiplication

Stops tumor growth

Common side-effects

Myelosuppression

Loss of hunger

Nausea

Vomiting

Mouth ulcers

Tiredness

Skin rashes

Hair loss

Serious side effects

Severe fall in Neutrophils

Fatal lung inflammation -Pneumonitis

QT prolongation

Elevated liver enzymes

Opportunistic infections -fungal, bacterial

Precautions:

To be used cautiously in patients with

Pre-existing lung disease

Liver dysfunctions

Renal dysfunctions

Blood disorders

Cardiac abnormalities

Contraindication -

Not to be used if any previous allergy or hypersensitivity to palbociclib or any excipients.

Breastfeeding mothers

Pregnant women

Warning

To be used under medical prescription only

Important Safety and Monitoring Information

Regular monitoring of the

Liver function - Elevated liver enzymes

Blood count- CBC count

Respiratory functions- interstitial lung disease

Cardiac functions- QT prolongation

Opportunistic infections- fungal, bacterial