Pegdoxine

Description

Pegdoxine injection

Pegdoxine injection (Doxorubicin Pegylated Liposomal) is used to treat many types of cancer such as ovarian cancer, AIDS-related Kaposi sarcoma, and multiple myeloma. This drug belongs to the class of antineoplastics (drugs used to fight cancer) known as anthracyclines. Injecting pegdoxine will slow or stop the growth of cancer cells. It is important that you take pegdoxine as prescribed by your doctor. The recommended dosage will be decided by your doctor based on your previous health and response to treatment. If you notice any signs or symptoms during treatment with pegdoxine, tell your doctor right away.

This Injection inhibits DNA and RNA synthesis by intercalating between DNA base pairs causing steric obstruction and inhibits topoisomerase-II at the point of DNA cleavage. Doxorubicin is also a powerful iron chelator. The iron-doxorubicin complex can bind DNA and cell membranes, producing free hydroxyl (OH) radicals that cleave DNA and cell membranes.

Doxorubicin Pegylated Liposomal Injection inhibits DNA and RNA synthesis by intercalating between DNA base pairs, resulting in steric obstruction, and inhibiting topoisomerase II at the point of DNA cleavage. It is also a strong iron chelator. The iron doxorubicin complex can bind to DNA and cell membranes and produce hydroxyl free radicals (OH) which cleave DNA and cell membranes. Doxorubicin is a pegylated composition that protects the liposomes, thereby increasing blood flow time.

Usage:

Injection of pegdoxine, a cancer drug used to treat multiple myeloma, ovarian cancer and Kaposi’s sarcoma (a type of cancer in which lesions grow under the surface of the skin, lymph nodes, etc.) This drug affects your immune system and makes your body weak to fight infection .Don’t get the wrong pegdoxine injection as it can cause serious side effects. It is recommended that you do not change your regular dosing schedule without taking your doctor’s advice. Follow your doctor’s instructions to avoid further complications.

Common Side Effects:

Injecting pegdoxine can interact with other drugs and increase the risk of side effects. Make sure you disclose your previous medical history and discuss it with doctor.

• Severe headache
• Sore throat
• Nausea
• Diarrhea
• Hair loss
• Cough
• Loss of appetite
• Shortness of breath
• Tiredness
• Chest pain
• Shortness of breath
• Irregular heartbeat
• Back pain
• Difficulty in urination
• Pale skin
• Dehydration

Contraindication:

Do not take this medication if you are allergic to pegylated doxorubicin.