Pemeaxis 500mg Injection

Description

PEMEAXIS 500mg Injection
Composition: Pemetrexed 500 mg
Category: Anticancer Medication

Overview
Pemeaxis is a chemotherapy drug primarily prescribed for the treatment of certain types of lung cancer.

Therapeutic Uses

• • Non-small cell lung cancer (NSCLC)

• • Malignant pleural mesothelioma

Mechanism of Action
Pemeaxis works by blocking folate metabolism within cancer cells, which disrupts DNA and RNA synthesis, thereby slowing or stopping cancer cell growth.

Precautions
Use with caution in patients who have:

• • Liver disease

• • Kidney disease

• • Blood-related disorders

Drug Interactions
Avoid combining with:

• • NSAIDs and other kidney-toxic drugs

• • Live vaccines

• • Anticancer Medications that interfere with folate metabolism

Possible Side Effects

Common:

• • Fatigue and weakness

• • Nausea and vomiting

• • Bone marrow suppression

• • Mouth sores

• • Reduced appetite

• • Diarrhea

• • Fluid retention

• • Hair thinning or loss

Serious:

• • Severe myelosuppression

• • Allergic (anaphylactic) reactions

• • Liver toxicity

• • Kidney damage

Contraindications
Do not use in:

• • Individuals allergic to its components

• • Pregnant or breastfeeding women

• • Patients with significant kidney impairment

• • People with severely low blood counts

Warnings & Recommendations

• • Use strictly under a doctor’s supervision.

• • Supplement with folic acid and vitamin B12 during treatment.

Monitoring During Therapy
Regularly check:

• • Complete blood count

• • Liver function tests

• • Kidney function tests

• • Hydration status

• • Electrolyte levels

Storage Instructions

• • Keep refrigerated at 2–8 °C

• • Protect from direct light

Administration Guidelines

• • Administer only as a slow intravenous infusion

• • Use immediately after reconstitution