Description
Tafnext 25mg
Composition : Tenofovir Alfenamide- 25mgÂ
Classification: Hepatitis B MedicineÂ
What is Tafnext?
It is an antiviral medicine that controls chronic Hepatitis B and HIV-1 infections.
Uses of TafnextÂ
• Chronic Hepatitis BÂ
• As a combination therapy in HIV-1 infectionsÂ
How does it work?
It inhibits the enzyme that causes viral replication and multiplication.
It causes natural viral cell death.
Benefits Â
• Targeted action, fewer side effectsÂ
• Significant viral suppressionÂ
• Lesser effect on kidney functions
• Improved liver functionsÂ
• Better bone mineral densityÂ
• Well toleratedÂ
Common side effectsÂ
Nausea, dizziness, headache, digestive issues, tiredness, diarrhea, and abdominal pain.
Serious side effectsÂ
• Lactic Acidosis – unusual pain, breathing issues, irregular heartbeats, abdominal pain.
• Irregular heartbeat – Arrhythmia
• Deep or rapid breathingÂ
• Enlarged fatty liverÂ
• Severely low phosphate levels cause muscle weaknessÂ
• Pale hands and feet (blue coloration)
• Dark urine, yellow eyes, pale stoolÂ
• Fluid retention-swelling of jointsÂ
• Sudden inflammatory reaction on starting the treatment.
PrecautionsÂ
To be used cautiously in patients with:Â
• Kidney disordersÂ
• HIV—Co-infectionsÂ
• Liver transplantÂ
• Elderly PatientsÂ
• Postmenopausal women
• People at risk of osteoporosisÂ
Contraindication—
• Not to be used if any previous allergy or hypersensitivity to tenovofir or any excipients.
• Breastfeeding mothersÂ
• Pregnant womenÂ
• It should not be used as monotherapy for HIV patientsÂ
WarningÂ
To be used under medical prescription onlyÂ
Important Safety and Monitoring InformationÂ
• Regular monitoring of the liver function, renal function, and bone density.
• Screen for viral load and HIV infections before treatment initiation.
• Hepatitis B flares, if the medicine is abruptly discontinued.
Treatment InstructionsÂ
• It must be taken consistently to get effective viral suppression.
• Missing doses increase the risk of relapse and drug resistance.



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