Tafnext

Tafnext

Composition: Tenofovir Alfenamide- 25mg

Classification: Hepatitis B Medicine

What is Tafnext?

It is an antiviral medicine that controls chronic Hepatitis B and HIV-1 infections.

Uses of Tafnext

Chronic Hepatitis B

As a combination therapy in HIV-1 infections

How does it work?

It inhibits the enzyme that causes viral replication and multiplication.

It causes natural viral cell death.

Benefits

Targeted action, fewer side effects

Significant viral suppression

Lesser effect on kidney functions

Improved liver functions

Better bone mineral density

Well tolerated

Common side effects

Nausea, dizziness, headache, digestive issues, tiredness, diarrhea, and abdominal pain.

Serious side effects

Lactic Acidosis - unusual pain, breathing issues, irregular heartbeats, abdominal pain.

Irregular heartbeat - Arrhythmia

Deep or rapid breathing

Enlarged fatty liver

Severely low phosphate levels cause muscle weakness

Pale hands and feet (blue coloration)

Dark urine, yellow eyes, pale stool

Fluid retention-swelling of joints

Sudden inflammatory reaction on starting the treatment.

Precautions

To be used cautiously in patients with

Kidney disorders

HIV -co-infections

Liver transplant

Elderly Patients

Postmenopausal women

People at risk of osteoporosis

Contraindication -

Not to be used if any previous allergy or hypersensitivity to tenovofir or any excipients.

Breastfeeding mothers

Pregnant women

It should not be used as monotherapy for HIV patients

Warning

To be used under medical prescription only

Important Safety and Monitoring Information

Regular monitoring of the liver function, renal function, and bone density.

Screen for viral load and HIV infections before treatment initiation.

Hepatitis B flares, if the medicine is abruptly discontinued.

Treatment Instructions

It must be taken consistently to get effective viral suppression.

Missing doses increases the risk of relapse and drug resistance