Tudobest-L

Tudobest-L

Composition:

Tenofovir fumarate - 300mg

Lamivudine-300mg

Classification: HIV medicine

What is Tudobest L?

Tudobest is a fixed-dose combination used for the treatment of Hepatitis B and HIV.

Uses of Tudobest L

HIV-1 infection

Chronic Hepatitis B

How does it work?

It mimics the DNA bases and blocks their multiplication and replication.

Causes chain termination

Cancer cell death

Benefits

Potent viral suppression

Improves immunity

Well tolerated

Less frequent dosing

Lowers the chances of resistance

Prevent disease progression and transmission

Common side effects

Nausea

Vomiting

Diarrhea

Skin rashes and ulcers

Lightheaded ness

Serious side effects

Lactic acidosis

Liver damage-yellowish skin, urine, jaundice

Kidney damage- urine changes, fluid retention.

Stomach pain - inflammation in the pancreas

Demineralization of bone- fractures, weakness, pain

Breathing difficulty, rash, swelling

Precautions

To be used cautiously in -

Reduced renal functions-kidney disorders.

Liver disorder

Osteoporosis

Elderly

Pregnant, lactating women

Co-infections (Hepatitis B)

Metabolic disorders

Important monitoring instructions

Liver functions

Kidney function

Bone mineral density

Lactic acid levels

Viral load and CD4 count

Contraindications

Severe liver dysfunction.

Hypersensitivity or allergic reaction to the drug or its excipients.

Warnings

To be used under medical prescription.

Do not stop medication immediately, as it causes hepatitis B flare up in co-infections.

Drug interactions

Anticonvulsant drugs

Cardiovascular drugs

Antihypertensive

Anti-fungal and

Anti-tubercular drugs