Abacavir + Lamivudine
Abacavir + Lamivudine
Classification: HIV medicine
What is Abacavir + Lamivudine?
It is a fixed-dose combination used for HIV – 1 treatment. Used as an adjuvant to other antiretrovirals.
Uses of Abacavir, Lamivudine Combination
- To treat HIV -1 infections
How does it work?
- The drug combination works by inhibiting viral replication and multiplication.
- Terminates DNA chain elongation
- Causes cell death
Benefits
- Significantly lowers viral load
- Improves immunity
- Inhibit transmission
- Delays disease progression
Common Side Effects
- Nausea
- GIT upset
- Reduced appetite
- Insomnia
- Diarrhea
- Skin rashes
Serious Side Effects
- Fatty liver – enlarged liver size
- Liver toxicity
- Lactic acidosis
- Pancreatitis
- Allergic reaction
Precautions of Abacavir + Lamivudine
To be cautiously used in people –
- Liver disorders
- Co-infections
- Kidney impairment
- Cardiovascular disorder
- Alcohol use due to liver toxicity
- Pregnant and breastfeeding women
Contraindications
- Severe liver dysfunction
- Hypersensitivity or allergy to drug components
Warnings
To be used under medical prescription.
Hepatitis B co-infections may cause serious viral flare-ups; do not stop medication immediately.
Important Monitoring Considerations
Check for –
- Lactic acidosis
- Liver function – elevated liver enzymes
- Viral loads (HIV, HBV)
- Pancreatitis
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Formulations based on "Abacavir + Lamivudine" (5)
Abakast-L
Abacavir & Lamivudine
Product Name Abakast-L Composition Abacavir (600mg) + Lamivudine (300mg) Manufactured By Aprazer Healthcare Pvt Ltd Dose/Strength 600 mg & 300 mg Packaging Size 30 Tablets Form Tablet Prescription Required Storage Store below 30°C
Abalam Tablet
Abacavir (600mg) + Lamivudine (300mg)
Product Name Abalam Tablet Composition Abacavir (600mg) + Lamivudine (300mg) Dose/Strength 600 mg & 300 mg Form Tablet Manufactured By Genix Lifescience Pvt Ltd Packaging Size 30 tablets Prescription Required Storage Store below 30°C
Inbec
Abacavir & Dolutegravir & Lamivudine
Product Name Inbec Composition Abacavir + Dolutegravir + Lamivudine Dose/Strength 600mg + 50mg + 300mg Packaging Size 30 Tablets Form Tablet Manufactured By Emcure Prescription Required Storage Store below 30°C
Albavir Tablet
Abacavir (600mg) + Lamivudine (300mg)
Product Name Albavir Tablet Composition Abacavir (600mg) + Lamivudine (300mg) Dose/Strength 600 mg & 300 mg Form Tablet Manufactured By Mylan Pharmaceuticals Pvt Ltd Packaging Size 30 tablets Prescription Required Storage Store below 30°C
Abamune L 600mg/300 mg Tablet
Abacavir & Lamivudine
Product Name Abamune L 600 mg/300mg Tablet Composition Abacavir (600mg) + Lamivudine (300mg) Dose/Strength 600 mg & 300 mg Form Tablet Manufactured By Cipla Packaging Size 30 tablets Prescription Required Storage Store below 30°C