Acalabrutinib

Classification - Anti-cancer medicine

What is Acalabrutinib?

It is a second-generation drug.

It is used to treat blood cancers.

It is a targeted cancer therapy drug.

Acalabrutinib uses -

It is used in -

Chronic leukemia

lymphoma

Mantle cell lymphoma

Acalabrutinib working -

It blocks the BTK enzyme.

It stops the formation of B lymphocytes (white blood cells).

It inhibits the malignancy of blood cells.

It slows down /inhibit blood cancer.

What are Acalabrutinib side effects?

The common side effects include -

Headache

Nausea

Diarrhea

Fatigue

Muscle/joint pain

Easy bruising

Skin rashes

UTI

Respiratory infections

Serious side effects -

Unusual bleeding

Severe infection

Irregular heartbeat

Anemia

Lowered platelets

Dark urine

Secondary cancers

What things must be considered while using Acalabrutinib?

It increases risk of bleeding and infection.

Avoid dental extractions.

Prevent infections

It can induce a hepatitis B flare in hepatitis B co-infection.

Do not move in direct sun.

Keep drinking water/fluids.

It causes dizziness; avoid driving.

It must be used carefully in -

Cardiac disorders

Advanced liver disorders

Active infections

What drugs must be avoided with Acalabrutinib?

It must be taken at a gap of 2 hours from antacids, H2 blockers, or PPIs.

Drugs that reduce drug excretion and increase drug buildup in the body.

It leads to several side effects and toxicity.

Antifungals

Antibiotics

HIV /Hepatitis B medicines

Heart medicines

Blood pressure medicines

Certain drugs increases risk of bleeding -

Blood thinners

Anti-coagulants

Pain killers

Drugs that reduce Acalabrutinib level in the body-

Anti-seizure drugs

Antibiotics

Prostate cancer drugs

What are the warnings with Acalabrutinib?

Do not use it in -

Allergy to the drug

Pregnancy/breastfeeding.

The drug dose must be monitored in case of -

Severe liver disorder

Severe infection

Surgery

What functions should be monitored with Acalabrutinib?

Regular monitoring is required -

Complete blood count

Liver function test

Hepatitis B screening

Blood pressure

Cardiovascular functions

Skin functions

Why choose Gandhi Medicos for Acalabrutinib?

Gandhi Medicos is a drug supplier and exporter.

We supply original, authentic drugs worldwide.

We are a recognized exporter of anticancer drugs.

We export a global range of oncology medicines.

Supplying an exclusive range of acalabrutinib, we are the trusted drug suppliers to the top hospitals and dispensaries.

Collaborating with the top brands, we supply the original/authentic drugs.

We are chosen for our quality attributes-

WHO-certified products

Authentic/original brands

Timely deliveries

Temperature-controlled shipment