Afatinib Dimaleate

Classification: Anticancer Medicine

What is Afatinib Diamleate?

It is an anticancer medicine used for lung cancer

Uses

No small lung cancer

Advanced NSLC

Recurrent lung cancer

Mutations of the EGFR genes

How does it work?

It blocks EGFR activity.

It stops its growth and multiplication of cancer cells

Causes starvation of cancer cells

Benefits of using Afatinib Diamleate

Strong irreversible binding

Broad spectrum of activity

Slow disease progression

Used in failed chemotherapy

Better tolerated than chemotherapy

Common side effects

Diarrheas

Skin and nail changes

Mouth ulcers

Nausea

GIT upset

Reduced appetite

Serious side effects

Liver dysfunctions

Cardiovascular complications

Kidney dysfunctions

Electrolyte imbalance

Severe dehydration

Lung toxicity - cough, difficulty in breathing

Blurred vision

Precautions:

To be used cautiously in patients with -

Kidney dysfunctions

Liver dysfunctions

Hypertension

Eye issues

Heart disorders

Elderly

Dehydrated - electrolyte imbalance

With diuretics and an EGFR inhibitor

Contraindications

Not to be used in patients-

Hypersensitivity or allergy to the drug composition.

Pregnant and breastfeeding women

Warnings

Prescription drug to be used under medical supervision.

Important safety and monitoring information

Blood pressure

Liver functions

Kidney functions

Lung functions

Skin irritation or rashes

Dehydration

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